Our group is interested in the development and application of statistical genetics in the field of cardiovascular diseases and pharmacogenomics.
One of the main projects in the group presently is the analysis of a genetic study on muscle pain related to statin-use in a case-control study of 4600 participants collected in 9 collaborating centres throughout Quebec. We are also in the process of starting the data collection for our pharmacogenomic study of warfarin, which aims to sample 2500 incident users in a prospective observational study in Quebec. We have also been involved in the analysis of pharmacogenomic sub-studies of three phase-3 clinical trials and one phase-2 trial related to treatment for cardiovascular disease and dyslipidemia.
We work in close collaboration with scientists at the Beaulieu-Saucier Pharmacogenomics Center at the Montreal Heart Institute. We also participate in productive collaborative efforts with clinicians and scientists at the Montreal Heart Institute, at the Universite de Montréal, University of British Columbia, Memorial University in Newfoundland, Dalhousie in Halifax, and abroad, with whom we collaborate on various statistical genetics applications including family-based genetic projects, animal and human genetic studies.