Publications

2015

Just for you lplp

Cardiovascular pharmacogenomics; state of current knowledge and implementation in practice. P. Shahabi, MP. Dubé Int. J. Cardiol.. 2015; 184:772-795 [BibTex]

Genetic markers associated with cutaneous adverse drug reactions to allopurinol: a systematic review. S. Jarjour, M. Barrette, V. Normand, JL. Rouleau, MP. Dubé, S. de Denus Pharmacogenomics. 2015; 16(7):755-67 [BibTex]

Comparison of sequencing based CNV discovery methods using monozygotic twin quartets. MA. Legault, S. Girard, LP. Lemieux Perreault, GA. Rouleau, MP. Dubé PLoS ONE. 2015; 10(3):e0122287 [BibTex]

Mutation burden of rare variants in schizophrenia candidate genes. SL. Girard, PA. Dion, CV. Bourassa, S. Geoffroy, P. Lachance-Touchette, A. Barhdadi, M. Langlois, R. Joober, MO. Krebs, MP. Dubé, GA. Rouleau PLoS ONE. 2015; 10(6):e0128988 [BibTex]

Pharmacogenomic Determinants of the Cardiovascular Effects of Dalcetrapib. JC. Tardif, É. Rhéaume, LP. Lemieux Perreault, JC. Grégoire, Y. Feroz Zada, G. Asselin, S. Provost, A. Barhdadi, D. Rhainds, PL. L Allier, R. Ibrahim, R. Upmanyu, EJ. Niesor, R. Benghozi, G. Suchankova, F. Laghrissi-Thode, MC. Guertin, AG. Olsson, I. Mongrain, GG. Schwartz, MP. Dubé Circ Cardiovasc Genet. 2015; [BibTex]

2014

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. I. Postmus, S. Trompet, HA. Deshmukh, MR. Barnes, X. Li, HR. Warren, DI. Chasman, K. Zhou, BJ. Arsenault, LA. Donnelly, KL. Wiggins, CL. Avery, P. Griffin, Q. Feng, KD. Taylor, G. Li, DS. Evans, AV. Smith, CE. de Keyser, AD. Johnson, AJ. de Craen, DJ. Stott, BM. Buckley, I. Ford, RG. Westendorp, PE. Slagboom, N. Sattar, PB. Munroe, P. Sever, N. Poulter, A. Stanton, DC. Shields, E. O\\\'Brien, S. Shaw-Hawkins, YD. Chen, DA. Nickerson, JD. Smith, MP. Dubé, SM. Boekholdt, GK. Hovingh, JJ. Kastelein, PM. McKeigue, J. Betteridge, A. Neil, PN. Durrington, A. Doney, F. Carr, A. Morris, MI. McCarthy, L. Groop, E. Ahlqvist, Welcome Trust Case Control Consortium, JC. Bis, K. Rice, NL. Smith, T. Lumley, EA. Whitsel, T. Stürmer, E. Boerwinkle, JS. Ngwa, CJ. O\\\'Donnell, RS. Vasan, WQ. Wei, RA. Wilke, CT. Liu, F. Sun, X. Guo, SR. Heckbert, W. Post, N. Sotoodehnia, AM. Arnold, JM. Stafford, J. Ding, DM. Herrington, SB. Kritchevsky, G. Eiriksdottir, LJ. Launer, TB. Harris, AY. Chu, F. Giulianini, JG. MacFadyen, BJ. Barratt, F. Nyberg, BH. Stricker, AG. Uitterlinden, A. Hofman, F. Rivadeneira, V. Emilsson, OH. Franco, PM. Ridker, V. Gudnason, Y. Liu, JC. Denny, CM. Ballantyne, JI. Rotter, L. Adrienne Cupples, BM. Psaty, CN. Palmer, JC. Tardif, HM. Colhoun, G. Hitman, RM. Krauss, J. Wouter Jukema, MJ. Caulfield Nat Commun. 2014; 5:5068 [BibTex]

Development of a broad-based ADME panel for use in pharmacogenomic studies.. AM. Brown, Y. Renaud, C. Ross, M. Hansen, I. Mongrain, D. Valois, BC. Carleton, MR. Hayden, MP. Dubé, JC. Tardif, MS. Phillips Pharmacogenomics. 2014; 15(9):1185-95 [BibTex]

Evaluation of links between high-density lipoprotein genetics, functionality, and aortic valve stenosis risk in humans.. BJ. Arsenault, MP. Dubé, MR. Brodeur, AB. de Oliveira Moraes, V. Lavoie, AE. Kernaleguen, S. Guauque-Olarte, P. Mathieu, P. Pibarot, D. Messika-Zeitoun, Y. Bossé, D. Rhainds, E. Rhéaume, JC. Tardif Arterioscler. Thromb. Vasc. Biol.. 2014; 34(2):457-62 [BibTex]

CKM and LILRB5 Are Associated with Serum Levels of Creatine Kinase.. MP. Dubé, R. Zetler, A. Barhdadi, A. Brown, I. Mongrain, V. Normand, N. Laplante, G. Asselin, Y. Feroz Zada, S. Provost, J. Bergeron, S. Kouz, R. Dufour, A. Diaz, S. deDenus, J. Turgeon, E. Rhéaume, MS. Phillips, JC. Tardif Circ Cardiovasc Genet. 2014; [BibTex]

Genetic markers of cisplatin-induced hearing loss in children.. BC. Carleton, CJ. Ross, K. Pussegoda, AP. Bhavsar, H. Visscher, JW. Lee, B. Brooks, SR. Rassekh, MP. Dubé, MR. Hayden Clin. Pharmacol. Ther.. 2014; 96(3):296-8 [BibTex]

Comparison of genotype clustering tools with rare variants.. LP. Perreault, MA. Legault, A. Barhdadi, S. Provost, V. Normand, JC. Tardif, MP. Dubé BMC Bioinformatics. 2014; 15:52 [BibTex]

Modifiers of (CAG)n instability in Machado-Joseph disease (MJD/SCA3) transmissions: an association study with DNA replication, repair and recombination genes. S. Martins, CE. Pearson, P. Coutinho, S. Provost, A. Amorim, MP. Dubé, J. Sequeiros, GA. Rouleau Hum. Genet.. 2014; 133(10):1311-8 [BibTex]

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits.. PL. Auer, A. Teumer, U. Schick, A. O\\\'Shaughnessy, KS. Lo, N. Chami, C. Carlson, S. de Denus, MP. Dubé, J. Haessler, RD. Jackson, C. Kooperberg, LP. Perreault, M. Nauck, U. Peters, JD. Rioux, F. Schmidt, V. Turcot, U. Völker, H. Völzke, A. Greinacher, L. Hsu, JC. Tardif, GA. Diaz, AP. Reiner, G. Lettre Nat. Genet.. 2014; 46(6):629-34 [BibTex]

Lipoprotein(a) levels, genotype, and incident aortic valve stenosis: a prospective mendelian randomization study and replication in a case-control cohort.. BJ. Arsenault, SM. Boekholdt, MP. Dubé, E. Rhéaume, NJ. Wareham, KT. Khaw, MS. Sandhu, JC. Tardif Circ Cardiovasc Genet. 2014; 7(3):304-10 [BibTex]

Validation of patient-reported warfarin dose in a prospective incident cohort study.. S. Dumas, E. Rouleau-Mailloux, A. Barhdadi, M. Talajic, JC. Tardif, MP. Dubé, S. Perreault Pharmacoepidemiol Drug Saf. 2014; 23(3):285-9 [BibTex]

Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity.. BC. Carleton, CJ. Ross, AP. Bhavsar, U. Amstutz, K. Pussegoda, H. Visscher, JW. Lee, B. Brooks, SR. Rassekh, MP. Dubé, MR. Hayden Clin. Pharmacol. Ther.. 2014; 95(3):253 [BibTex]

2013

pyGenClean: efficient tool for genetic data clean up before association testing.. LP. Lemieux Perreault, S. Provost, MA. Legault, A. Barhdadi, MP. Dubé Bioinformatics. 2013; 29(13):1704-5 [BibTex]

The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans.. RR. Singaraja, S. Sivapalaratnam, K. Hovingh, MP. Dubé, J. Castro-Perez, HL. Collins, SJ. Adelman, M. Riwanto, J. Manz, B. Hubbard, I. Tietjen, K. Wong, LJ. Mitnaul, M. van Heek, L. Lin, TA. Roddy, J. McEwen, G. Dallinge-Thie, L. van Vark-van der Zee, G. Verwoert, M. Winther, C. van Duijn, A. Hofman, MD. Trip, AD. Marais, B. Asztalos, U. Landmesser, E. Sijbrands, JJ. Kastelein, MR. Hayden Circ Cardiovasc Genet. 2013; 6(1):54-62 [BibTex]

Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children.. K. Pussegoda, CJ. Ross, H. Visscher, M. Yazdanpanah, B. Brooks, SR. Rassekh, YF. Zada, MP. Dubé, BC. Carleton, MR. Hayden, CPNDS Consortium Clin. Pharmacol. Ther.. 2013; 94(2):243-51 [BibTex]

Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent.. F. Aminkeng, CJ. Ross, SR. Rassekh, LR. Brunham, J. Sistonen, MP. Dube, M. Ibrahim, TB. Nyambo, SA. Omar, A. Froment, JM. Bodo, S. Tishkoff, BC. Carleton, MR. Hayden Pharmacogenomics J.. 2013; [BibTex]

Institutional profile: the Beaulieu-Saucier Université de Montréal Pharmacogenomics Centre at the Montreal Heart Institute.. MP. Dubé, JC. Tardif Pharmacogenomics. 2013; 14(2):131-6 [BibTex]

Risk of congenital heart defects is influenced by genetic variation in folate metabolism.. KE. Christensen, YF. Zada, CV. Rohlicek, GU. Andelfinger, JL. Michaud, JL. Bigras, A. Richter, MP. Dubé, R. Rozen Cardiol Young. 2013; 23(1):89-98 [BibTex]

2012

Rare copy number variants contribute to congenital left-sided heart disease.. MP. Hitz, LP. Lemieux-Perreault, C. Marshall, Y. Feroz-Zada, R. Davies, SW. Yang, AC. Lionel, G. D\\\'Amours, E. Lemyre, R. Cullum, JL. Bigras, M. Thibeault, P. Chetaille, A. Montpetit, P. Khairy, B. Overduin, S. Klaassen, P. Hoodless, M. Nemer, AF. Stewart, C. Boerkoel, SW. Scherer, A. Richter, MP. Dubé, G. Andelfinger PLoS Genet.. 2012; 8(9):e1002903 [BibTex]

Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol.. I. Tietjen, GK. Hovingh, RR. Singaraja, C. Radomski, A. Barhdadi, J. McEwen, E. Chan, M. Mattice, A. Legendre, PL. Franchini, MP. Dubé, JJ. Kastelein, MR. Hayden PLoS ONE. 2012; 7(8):e37437 [BibTex]

Pooled DNA resequencing of 68 myocardial infarction candidate genes in French canadians.. M. Beaudoin, KS. Lo, A. N\\\'Diaye, MA. Rivas, MP. Dubé, N. Laplante, MS. Phillips, JD. Rioux, JC. Tardif, G. Lettre Circ Cardiovasc Genet. 2012; 5(5):547-54 [BibTex]

Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice.. SA. Wiltshire, E. Diez, Q. Miao, MP. Dubé, M. Gagné, O. Paquette, RG. Lafrenière, M. Ndao, LW. Castellani, E. Skamene, SM. Vidal, A. Fortin Physiol. Genomics. 2012; 44(17):843-52 [BibTex]

Tacrolimus-induced nephrotoxicity and genetic variability: a review.. VM. Gijsen, P. Madadi, MP. Dube, DA. Hesselink, G. Koren, SN. de Wildt Ann. Transplant.. 2012; 17(2):111-21 [BibTex]

A novel PLP1 mutation further expands the clinical heterogeneity at the locus.. CK. Hand, G. Bernard, MP. Dubé, MI. Shevell, GA. Rouleau Can J Neurol Sci. 2012; 39(2):220-4 [BibTex]

PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients.. K. Lachance, A. Barhdadi, I. Mongrain, V. Normand, M. Zakrzewski, MH. Leblanc, N. Racine, M. Carrier, A. Ducharme, J. Turgeon, MP. Dubé, MS. Phillips, M. White, S. de Denus Pharmacogenet. Genomics. 2012; 22(5):336-43 [BibTex]

Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children.. H. Visscher, CJ. Ross, SR. Rassekh, A. Barhdadi, MP. Dubé, H. Al-Saloos, GS. Sandor, HN. Caron, EC. van Dalen, LC. Kremer, HJ. van der Pal, AM. Brown, PC. Rogers, MS. Phillips, MJ. Rieder, BC. Carleton, MR. Hayden, Canadian Pharmacogenomics Network for Drug Safety Consortium J. Clin. Oncol.. 2012; 30(13):1422-8 [BibTex]

Validation of warfarin pharmacogenetic algorithms in clinical practice.. M. Marin-Leblanc, S. Perreault, I. Bahroun, M. Lapointe, I. Mongrain, S. Provost, J. Turgeon, M. Talajic, R. Brugada, M. Phillips, JC. Tardif, MP. Dubé Pharmacogenomics. 2012; 13(1):21-9 [BibTex]

2011

Association between renal function and CYP3A5 genotype in heart transplant recipients treated with calcineurin inhibitors.. S. de Denus, M. Zakrzewski, A. Barhdadi, MH. Leblanc, N. Racine, F. Bélanger, M. Carrier, A. Ducharme, MP. Dubé, J. Turgeon, M. White J. Heart Lung Transplant.. 2011; 30(3):326-31 [BibTex]

Familial ventricular aneurysms and septal defects map to chromosome 10p15.. N. Tremblay, SW. Yang, MP. Hitz, G. Asselin, J. Ginns, K. Riopel, R. Gendron, A. Montpetit, E. Duhig, MP. Dubé, D. Radford, G. Andelfinger Eur. Heart J.. 2011; 32(5):568-73 [BibTex]

Mutations in a novel serine protease PRSS56 in families with nanophthalmos.. A. Orr, MP. Dubé, JC. Zenteno, H. Jiang, G. Asselin, SC. Evans, A. Caqueret, H. Lakosha, L. Letourneau, J. Marcadier, M. Matsuoka, C. Macgillivray, M. Nightingale, S. Papillon-Cavanagh, S. Perry, S. Provost, M. Ludman, DL. Guernsey, ME. Samuels Mol. Vis.. 2011; 17:1850-61 [BibTex]

Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec.. MP. Dubé, JL. Bigras, M. Thibeault, N. Bureau, P. Chetaille, A. Richter, J. Mercier, M. Bellavance, C. Rohlicek, R. Rozen, M. Nemer, P. Khairy, R. Gendron, G. Andelfinger Cardiol Young. 2011; 21(6):654-64 [BibTex]

Fetal alcohol spectrum disorders: gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes.. JN. Reynolds, J. Weinberg, S. Clarren, C. Beaulieu, C. Rasmussen, M. Kobor, MP. Dube, D. Goldowitz Semin Pediatr Neurol. 2011; 18(1):49-55 [BibTex]

2010

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura. Lafrenière RG, Cader MZ, Poulin JF, Andres-Enguix I, Simoneau M, Gupta N, Boisvert K, Lafrenière F, McLaughlan S, Dubé MP, Marcinkiewicz MM, Ramagopalan S, Ansorge O, Brais B, Sequeiros J, Pereira-Monteiro JM, Griffiths LR, Tucker SJ, Ebers G, Rouleau GA Nat Med.. 2010; 16(10):1157-60

Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts. Awadalla P, Gauthier J, Myers RA, Casals F, Hamdan FF, Griffing AR, Côté M, Henrion E, Spiegelman D, Tarabeux J, Piton A, Yang Y, Boyko A, Bustamante C, Xiong L, Rapoport JL, Addington AM, Delisi JL, Krebs MO, Joober R, Millet B, Fombonne E, Mottron L, Zilversmit M, Keebler J, Daoud H, Marineau C, Roy-Gagnon MH, Dubé MP, Eyre-Walker A, Drapeau P, Stone EA, Lafrenière RG, Rouleau GA. Am J Hum Genet.. 2010; 87(3):316-24 [BibTex]

Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1 (tyrosinase-related protein 1). Fortin A, Diez E, Ritchie J, Sotocinal SG, Dubé MP, Gagne M, Paquette O, Skamene E, Mogil JS. Genes Brain Behav.. 2010; 9(8):856-67 [BibTex]

Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases. Xiong L, Montplaisir J, Desautels A, Barhdadi A*, Turecki G, Levchenko A, Thibodeau P, Dubé MP, Gaspar C, Rouleau GA Arch Neurol.. 2010; 67(5):617-22 [BibTex]

Partitioning of copy-number genotypes in pedigrees. Lemieux Perreault LP*, Andelfinger G, Asselin G*, Dubé MP* BMC Bioinformatics. 2010; 11(226) [BibTex]

Mutations in DCC Cause Congenital Mirror Movements. Srour M, Rivière JB, Pham JMT, Dubé MP*, Girard S, Morin S, Dion PA, Asselin G*, Rochefort D, Hince P, Diab S, Sharafaddinzadeh N, Chouinard S, Théoret H, Charron F, Rouleau GA. Science. 2010; 328(597):592 [BibTex]

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Gauthier J, Champagne N, Lafrenière RG, Xiong L, Spiegelman D, Brustein E, Lapointe M, Peng H, Côté M, Noreau A, Hamdan FF, Addington AM, Rapoport JL, Delisi LE, Krebs MO, Joober R, Fathalli F, Mouaffak F, Haghighi AP, Néri C, Dubé MP*, Samuels ME, Marineau C, Stone EA, Awadalla P, Barker PA, Carbonetto S, Drapeau P, Rouleau GA; the S2D Team. Proc Natl Acad Sci U S A. 2010; [BibTex]

Genetic determinants of blood pressure reduction following potassium supplementation : and the candidates are?. deDenus S, Dubé MP* Journal of Hypertension. 2010; 28(4):668-670

Genome-wide TDT analysis in French-Canadian families with Tourette syndrome. Rivière JB, St-Onge J, Gaspar C, Diab S, Dion Y, Lespérance P, Tellier G, Richer F, Chouinard S, Dubé MP*, Rouleau GA. Montreal Tourette Study Group Can J Neurol Sci. 2010; 37(1):110-2 [BibTex]

Genetics of bronchopulmonary dysplasia in the age of genomics. Lavoie P, Dubé MP* Current Opinion in Pediatrics. 2010; 22(2):134-8 [BibTex]

Testing for Gene-Gene Interaction with AMMI Models. Barhdadi A, Dubé MP* Statistical Applications in Genetics and Molecular Biology 2010. 2010; 9(1)[URL]

Novel mutations in the sacsin gene in ataxia patients from Maritime Canada. Guernsey DL, Dubé MP*, Jiang H, Asselin G*, Blowers S, Evans S, Ferguson M, Macgillivray C, Matsuoka M, Nightingale M, Rideout A, Delatycki M, Orr A, Ludman M, Dooley J, Riddell C, Samuels ME. J Neurol Sci. 2010; 288(1-2):79-87 [BibTex]

2009

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Ross CJ, Katzov-Eckert H, Dubé MP, Brooks B, Rassekh SR, Barhdadi A*, Feroz-Zada Y*, Visscher H, Brown AM, Rieder MJ, Rogers PC, Phillips MS, Carleton BC, Hayden MR; the CPNDS Consortium. Nature Genetics. 2009; 41(12):1345-9 [BibTex]

Different models and single-nucleotide polymorphisms signal the simulated weak gene-gene interaction for a quantitative trait using haplotype-based and mixed models testing. Kovac IP*, Dubé MP* BMC Proc.. 2009; 15(3) [BibTex]

The challenge of detecting epistasis (GxG Interactions): Genetic Analysis Workshop 16. An P, Mukherjee O, Chanda P, Yao L, Engelman CD, Huang CH, Zheng T, Kovac IP*, Dubé MP*, Liang X, Li J, de Andrade M, Culverhouse R, Malzahn D, Manning AK, Clarke GM, Jung J, Province MA. Genet Epidemiol. 2009; 33(S1):S58-S67 [BibTex]

Application of principal component analysis to pharmacogenomic studies in Canada. Visscher H, Ross CJ, Dubé MP*, Brown AM, Phillips MS, Carleton BC, Hayden MR Pharmacogenomics J. 2009; [BibTex]

Association between cervical and intracranial dimensions and syringomyelia in the cavalier King Charles spaniel. Carruthers H, Rusbridge C, Dubé MP*, Holmes M, Jeffery N J Small Anim Pract.. 2009; 50(8):394-8 [BibTex]

Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2. Guernsey DL, Jiang H, Evans SC, Ferguson M, Matsuoka M, Nightingale M, Rideout AL, Provost S*, Bedard K, Orr A, Dubé MP*, Ludman M, Samuels ME. Am J Hum Genet.. 2009; 85(1):120-9 [BibTex]

Genetic Modulation of Brugada Syndrome by a Common Polymorphism. Lizotte E, Junttila MJ, Dubé MP*, Hong K, Benito B, DE Zutter M, Henkens S, Sarkozy A, Huikuri HV, Towbin J, Vatta M, Brugada P, Brugada J, Brugada R J Cardiovasc Electrophysiol. 2009; [BibTex]

Application of Homozygosity Haplotype Analysis to Genetic Mapping with High-Density SNP Genotype Data. Jiang H, Orr A, Guernsey DL, Robitaille J, Asselin G*, Samuels ME, Dubé MP* PLoS ONE. 2009; 4(4) [BibTex]

Genetic predictors of depressive symptoms in cardiac patients. McCaffery JM, Duan QL, Frasure-Smith N, Barhdadi A*, Lespérance F, Théroux P, Rouleau GA, Dube MP* Am J Med Genet B Neuropsychiatr Genet. 2009; 150(3):381-8 [BibTex]

Autosomal-dominant locus for restless legs syndrome in French-Canadians on chromosome 16p12.1.. Levchenko A, Montplaisir JY, Asselin G*, Provost S*, Girard SL, Xiong L, Lemyre E, St-Onge J, Thibodeau P, Desautels A, Turecki G, Gaspar C, Dubé MP*, Rouleau GA. Mov Discord. 2009; 24(1):40-50 [BibTex]

2008

Génome Québec & Montreal Heart Institute Pharmacogenomics Centre: a translational pharmacogenomics platform--from R&D to the clinic. Phillips MS, Hihi AK, van Rooij T, Smith AC, James S, Marsh S, Laplante N, Dubé MP*, Tardif JC. Pharmacogenomics. 2008; 9(10):1391-6 [BibTex]

Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Piton A, Michaud JL, Peng H, Aradhya S, Gauthier J, Mottron L, Champagne N, Lafrenière RG, Hamdan FF; S2D team; Joober R, Fombonne E, Marineau C, Cossette P, Dubé MP*, Haghighi P, Drapeau P, Barker PA, Carbonetto S, Rouleau GA Hum Mol Genet. 2008; 17(24):3965-74 [BibTex]

A survey of the personalized medicine landscape. Ozdemir V, Dubé MP*, Tardif JC, de Denus S, Phillips M, Stenne R, Shimoda K, Someya T, Godard B. Pharmacogenomics. 2008; 9(7):819-823 [BibTex]

Effects of AGTR1 A1166C Gene Polymorphism in Patients with Heart Failure Treated with Candesartan. de Denus S, Zakrzewski-Jakubiak M, Dubé MP*, Bélanger F, Lepage S, Leblanc MH, Gossard D, Ducharme A, Racine N, Whittom L, Lavoie J, Touyz RM, Turgeon J, White M Ann Pharmacother.. 2008; [BibTex]

A novel locus for idiopathic generalized epilepsy in French-Canadian families maps to 10p11. Kinirons P, Verlaan DJ, Dubé MP*, Poirier J, Deacon C, Lortie A, Clément JF, Desbiens R, Carmant L, Cieuta-Walti C, Shevell M, Rouleau GA, Cossette P Am J Med Genet A. 2008; 146(5):578-84 [BibTex]

Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure. Zakrzewski-Jakubiak M, de Denus S, Dubé MP*, Bélanger F, White M, Turgeon J. Br J Clin Pharmacol.. 2008; 65(5):742-51 [BibTex]

No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans. Bolduc V, Chagnon P, Provost S, Dube MP*, Belisle C, Gingras M, Mollica L, Busque L J Clin Invest. 2008; 118(1):333-41

2007

Two-stage strategies to detect gene x gene interactions in case-control data. Barhdadi A*, Dube MP* BMC proceedings. 2007; Suppl 1(S13) [BibTex]

Multistage Designs in the Genomic Era: Providing Balance in Complex Disease Studies. Dube MP*, Schmidt S, Hauser E Genetic Epidemiology. 2007; 31(S1):S1-S6 [BibTex]

Genetics of Congenital Amusia (or tone-deafness): A Family Aggregation Study. I Peretz, S Cummings, MP Dubé* American Journal of Human Genetics. 2007; 81(3):582-8

Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. Orr A, Dubé MP*, Marcadier J, Jiang H, Federico A, George S, Seamone C, Andrews D, Dubord P, Holland S, Provost S, Mongrain V, Evans S, Higgins B, Bowman S, Guernsey D, Samuels M PLoS ONE. 2007; 2(1) [BibTex]

Syringomyelia in cavalier King Charles spaniels: the relationship between syrinx dimensions and pain.. Rusbridge C, Carruthers H, Dubé MP*, Holmes M, Jeffery ND J Small Anim Pract. 2007; 48(8):432-6 [BibTex]

Loss-of-function mutations in the Nav1. 7 gene underlie congenital indifference to pain in multiple human populations. Goldberg YP, MacFarlane J, MacDonald ML, Thompson J, MP Dubé*, Mattice M, Fraser R, Young C, Hossain S, Pape T, Payne B, Radomski C, Donaldson G, Ives E, Cox J, Younghusband HB, Green R, Duff A, Boltshauser E, Grinspan GA, Dimon JH, Sibley BG, Andria G, Toscano E, Kerdraon J, Bowsher D, Pimstone SN, Samuels ME, Sherrington R, Hayden MR Clin Genet. 2007; 71(4):311-9 [BibTex]

New Technologies in Human Genetic Analysis. ME Samuels, B Higgins, S Provost, J Marcadier, C Blouin, S Bowman, MP Dubé* American Biotechnology Laboratory. 2007; 25(5):22-28

Gene-Gene Interaction Tests Using SVM and Neural Network Modeling. N Martchenko-Shimko*, MP Dubé* Computational Intelligence in Bioinformatics and Computational Biology. 2007;

Additive effects of obesity and TCF7L2 variants on risk for type 2 diabetes among cardiac patients. QL Duan, MP Dubé*, F Lesperance, P Théroux, J St-Onge, GA,N Frasure-Smith, A Barhdadi*, Rouleau, J McCaffery Diabetes Care. 2007; 30(6):1621-3 [BibTex]

Lamin A/C mutations associated with familial and sporadic cases of dilated cardiomyopathy in Koreans. K Song, MP Dubé*, J Lim, I Hwang, I Lee, JJ Kim Exp Mol Med.. 2007; 39(1):114-120 [BibTex]

2006

Autism spectrum disorders associated with X chromosome markers in French-Canadian males. J Gauthier, R Joober, M-P Dubé*, J St-Onge, A Bonnel, D Gariépy, S Laurent, R Najafee, H Lacasse, L St-Charles, É Fombonne, L Mottron, G A Rouleau Molecular Psychiatry. 2006; 11(2):206-213 [BibTex]

Common Genetic Vulnerability to Depressive Symptoms and Coronary Artery Disease: A Review and Development of Candidate Genes Related to Inflammation and Serotonin. M McCaffery, N Frasure-Smith, MP Dubé*, P Theroux, GA Rouleau, QL Duan, F Lesperance Psychosomatic Medicine. 2006; 68(2):187-200 [BibTex]

Human Monogenic Disorders- a Source of Novel Drug Targets. RR Brinkman, M-P Dubé*, GA Rouleau, A Orr, ME Samuels Nature Reviews Genetics. 2006; 7:249-260 [BibTex]

A new locus for autosomal dominant intracranial aneurysm, ANIB4, maps to chromosome 5p15. 2-14. 3. DJ Verlaan, MP Dubé*, J St-Onge, A Noreau, J Roussel, N Satgé, MC Wallace, GA Rouleau Journal Of Medical Genetics. 2006; 43(6):e31 [BibTex]

A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13. A Levchenko, S Provost*, JY Montplaisir, L Xiong, J St-Onge, P Thibodeau, JB Riviere, A Desautels, G Turecki, MP Dubé*, GA Rouleau Neurology. 2006; 67(5):900-1 [BibTex]

Bootstrap Inference with Neural-Network Modeling for Gene-Disease Association Testing. N Martchenko-Shimko, MP Dubé* Computational Intelligence in Bioinformatics and Computational Biology. 2006;

2005

Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region. E Shink, M Harvey, M Tremblay, B Gagné, P Belleau, C Raymond, M Labbé, MP Dubé*, RG Lafrenière, N Barden American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics. 2005; 135B(1):50-58 [BibTex]

A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors. QL Duan, B Nikpoor, M-P Dubé*, G Molinaro, IA Meijer, P Dion, D Rochefort, J Saint-Onge, L Flury, NJ Brown, JV Gainer, JL Rouleau, A Agostoni, M Cugno, P Simon, P Clavel, J Potier, B Wehbe, S Benarbia, J Marc-Aurèle, J Chanard, T Foroud, A Adam, GA Rouleau American Journal of Human Genetics. 2005; 77(4):617-626 [BibTex]

Chromosome 11-q24 region in Tourette Syndrome: Association and linkage disequilibrium study in the French Canadian population. A Díaz-Anzaldúa, J-B Rivière, M-P Dubé*, R Joober, J Saint-Onge, Y Dion, P Lespérance, F Richer, S Chouinard, G A Rouleau and the Montreal Tourette Syndrome Study Group The American Journal of Medical Genetics. 2005; 138A(3):225-228 [BibTex]

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