Marc-André Legault
Marc-André is a PhD student in bioinformatics at Université de Montréal. His research focuses on drug target genetics and the development of bioinformatics and statistical software.
He worked on creating large-scale cardiovascular events and GWAS summary statistics databases. He is also interested in the application of Mendelian randomization methods for drug target validation and randomized clinical trial optimization.
Selected Publications
- A genetic model of ivabradine recapitulates results from randomized clinical trials. Legault, Marc-André, Sandoval, Johanna, Provost, Sylvie, Barhdadi, Amina, Lemieux Perreault, Louis-Philippe, Shah, Sonia, Lumbers, R Thomas, de Denus, Simon, Tyl, Benoit, Tardif, Jean-Claude and Dubé, Marie-Pierre. PLoS One 2020; 7: e0236193. [BibTeX]
- Pharmacogenomics of blood lipid regulation. Legault, Marc-André, Tardif, Jean-Claude and Dubé, Marie-Pierre. Pharmacogenomics 2018; 7: 651-665. [BibTeX]
- Comparison of sequencing based CNV discovery methods using monozygotic twin quartets. Legault, Marc-André, Girard, Simon, Lemieux Perreault, Louis-Philippe, Rouleau, Guy A and Dubé, Marie-Pierre. PLoS One 2015; 3: e0122287. [BibTeX]