Audrey Lemaçon

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Audrey a rejoint notre groupe en juin 2019. Elle a effectué une Licence professionnelle en biotechnologie à l'Université Pierre & Marie Curie (P6, France) ainsi qu'un Master en bio-informatique au sein de l'Université de Rouen (France). Elle a poursuivi par un doctorot au programme de médecine moléculaire de l'Université Laval. Son projet de recherche a porté sur la susceptibilité génétique au cancer du sein. Elle est maintenant stagiaire post-doctorale au sein de notre groupe.

Bibliographie

  • Two single-nucleotide polymorphisms in the human vitamin D receptor promoter change protein--DNA complex formation and are associated with height and vitamin D status in adolescent girls. d'Alésio, Arnold, Garabédian, Michele, Sabatier, Jean Pierre, Guaydier-Souquieres, Genevieve, Marcelli, Christian, Lemaçon, Audrey, Walrant-Debray, Odile and Jehan, Frédéric. Human molecular genetics 2005; 22: 3539-3548.
  • Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22. 3. Hamdi, Yosr, Soucy, Penny, Kuchenbaeker, Karoline B, Pastinen, Tomi, Droit, Arnaud, Lemaçon, Audrey, Adlard, Julian, Aittomäki, Kristiina, Andrulis, Irene L, Arason, Adalgeir and others. Breast cancer research and treatment 2017; 1: 117-134.
  • Metagene profiles analyses reveal regulatory element’s factor-specific recruitment patterns. Beauparlant, Charles Joly, Lamaze, Fabien C, Deschênes, Astrid, Samb, Rawane, Lemaçon, Audrey, Belleau, Pascal, Bilodeau, Steve and Droit, Arnaud. PLoS computational biology 2016; 8: e1004751.
  • VEXOR: an integrative environment for prioritization of functional variants in fine-mapping analysis. Lemaçon, Audrey, Joly Beauparlant, Charles, Soucy, Penny, Allen, Jamie, Easton, Douglas, Kraft, Peter, Simard, Jacques and Droit, Arnaud. Bioinformatics 2017; 9: 1389-1391.
  • Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21. Hamdi, Yosr, Soucy, Penny, Adoue, Véronique, Michailidou, Kyriaki, Canisius, Sander, Lemaçon, Audrey, Droit, Arnaud, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker and others. Oncotarget 2016; 49: 80140.
  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Milne, Roger L, Kuchenbaecker, Karoline B, Michailidou, Kyriaki, Beesley, Jonathan, Kar, Siddhartha, Lindström, Sara, Hui, Shirley, Lemaçon, Audrey, Soucy, Penny, Dennis, Joe and others. Nature genetics 2017; 12: 1767.
  • Association analysis identifies 65 new breast cancer risk loci. Michailidou, Kyriaki, Lindström, Sara, Dennis, Joe, Beesley, Jonathan, Hui, Shirley, Kar, Siddhartha, Lemaçon, Audrey, Soucy, Penny, Glubb, Dylan, Rostamianfar, Asha and others. Nature 2017; 7678: 92.
  • Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes. Fachal, Laura, Aschard, Hugues, Beesley, Jonathan, Barnes, Daniel, Allen, Jamie, Kar, Siddhartha, Pooley, Karen, Dennis, Joe, Michailidou, Kyriaki, Turman, Constance and others. bioRxiv 2019: 521054.
  • DSNetwork: An integrative approach to visualize predictions of variants’ deleteriousness. Lemaçon, Audrey, Scott-Boyer, Marie-Pier, Ongaro-Carcy, Régis, Soucy, Penny, Simard, Jacques and Droit, Arnaud. Frontiers in Genetics 2020: 1349.
  • LD-Annot: a bioinformatics tool to automatically provide candidate SNPs with annotations for genetically linked genes. Prunier, Julien, Lemaçon, Audrey, Bastien, Alexandre, Jafarikia, Mohsen, Porth, Ilga Mercedes, Robert, Claude and Droit, Arnaud. Frontiers in Genetics 2019: 1192.
  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Fachal, Laura, Aschard, Hugues, Beesley, Jonathan, Barnes, Daniel R, Allen, Jamie, Kar, Siddhartha, Pooley, Karen A, Dennis, Joe, Michailidou, Kyriaki, Turman, Constance and others. Nature Genetics 2020: 1-18.