Lab's current projects

  • Canada Research Chair in Precision Medicine Data Analysis, 2020-2027, funded by SPIIE, PI: Marie-Pierre Dubé.
  • Recherche en médecine de précision portant sur le diabète et les maladies cardiovasculaires, 2019-2020, funded by CFI, PI: Marie-Pierre Dubé.
  • Mendelian randomization study of CETP and ADCY9 in cardiovascular disease, 2019-2020, funded by CIHR, PI: Marie-Pierre Dubé.
  • Study of the effect of sex on drugs dosing, concentrations and pharmacogenomics, 2020-2026, funded by CIHR, PIs: Simon de Denus, Marie-Pierre Dubé, Grégoire Leclair.
  • Determining the etiologies of age-related clonal hematopoiesis (ARCH), a new biomarker of cancer and cardiovascular disease development: focus on the roles of inflammation and genetic predisposition, 2019-2024, funded by CIHR, PIs: Lambert Busque, Jean-Claude Tardif, Marie-Pierre Dubé.
  • Pharmacogenomic substudy of COLCORONA, 2020-2025, PIs : Marie-Pierre Dubé, Jean-Claude Tardif.
  • Host-genomics in COVID-19, 2020-2025, funded by the Montreal Heart Institute Foundation, PI : Marie-Pierre Dubé.

Collaborations

  • Complex genetics of hypertrophic cardiomyopathy: Towards an integration of polygenic risk in clinical care, 2020-2026, funded by CIHR, PI: Rafik Tadros, co-investigator: Marie-Pierre Dubé.
  • Comparing the effects of cognitive training and physical exercise on cognition, cerebral autoregulation and cerebral vasoreactivity in men and women with heart failures, 2019-2024, funded by CIHR, PI: Louis Bherer, co-investigator: Marie-Pierre Dubé.
  • Développement d'un modèle de prédiction pour optimiser l'usage des anticoagulants oraux (DOACs) en pratique clinique, 2017-2021, funded by FRQS, PI: Sylvie Perreault, co-investigator: Marie-Pierre Dubé.
  • Effectiveness and safety of Direct Oral AntiCoagulants (DOACs) among older adults with atrial fibrillation, 2017-2020, funded by Heart and Stroke Foundation of Canada, PI: Sylvie Perreault, co-investigator: Marie-Pierre Dubé.
  • Inherited chromosomally-integrated human herpesvirus 6 and cardiovascular diseases, 2016-2020, funded by Heart and Stroke Foundation of Canada, PI: Louis Flamand, co-investigator: Marie-Pierre Dubé.
  • Projet ARCHI pour la mise en place d'une plateforme nationale d'accès et d'échanges responsables des données génomiques et clinico-administratives à des fins d'études et de recherches, 2018-2020, funded by Ministry of Economy, Science and Innovation, PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.
  • International Leadership in Precision Medicine Clinical Studies, 2018-2022, funded by the Ministère de l'Économie et de l'Innovation and the Fonds d’accélération des collaborations en santé (FACS), PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.
  • Curbing Atherosclerosis Through Precision Medicine, 2018-2022, funded by the Ministère de l'Économie et de l'Innovation and the Fonds d’accélération des collaborations en santé (FACS), PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.

Past projects (non-exhaustive)

  • Subvention FICM, 2015-2018, funded by Montreal Heart Institute Foundation, PI: Marie-Pierre Dubé.
  • Colchicine Cardiovascular Outcomes Trial, 2017-2018, funded by CIHR, PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.
  • Programme ARTERIA: Personnalisation des diagnostics et thérapies cardiovasculaires, 2014-2018, funded by Ministry of Finance, PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.
  • Pharmacogenomic testing of atorvastatin efficacy and toxicity in secondary prevention of cardiovascular diseases, 2013-2018, funded by CIHR, PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.
  • Colchicine Cardiovascular Outcomes Trialn, 2016-2017, funded by CIHR, PI: Jean-Claude Tardif, co-investigator: Marie-Pierre Dubé.
  • Études pharmacogénomiques vers une thérapie personnalisée en cardiologie, 2015-2017, funded by FRQS, PI: Marie-Pierre Dubé.
  • Personalized medicine strategies for molecular diagnostics and targeted therapeutics of cardiovascular diseases, 2013-2017, funded by Genome Canada, PI: Marie-Pierre Dubé
  • Genomic study of bleeding risk with warfarin, 2013-2017, funded by CIHR, PI: Marie-Pierre Dubé