Pour une liste complète des publications, référez-vous à PubMed.

2020

  • A genetic model of ivabradine recapitulates results from randomized clinical trials. Legault, M. A., Sandoval, J., Provost, S., Barhdadi, A., Lemieux Perreault, L. P., Shah, S., Lumbers, R. T., de Denus, S., Tyl, B., Tardif, J. C. and Dubé, M. P. . PLoS ONE 2020; 7: e0236193. [BibTeX]
  • Spironolactone metabolite concentrations in decompensated heart failure: insights from the ATHENA-HF trial. de Denus, S., Leclair, G., Dubé, M. P., St-Jean, I., Zada, Y. F., Oussaïd, E., Jutras, M., Givertz, M. M., Mentz, R. J., Tang, W. H. W., Ferreira, J. P., Rouleau, J., Butler, J. and Kalogeropoulos, A. P. . Eur. J. Heart Fail. 2020. [BibTeX]
  • CYP2D6 polymorphism and its impact on the clinical response to metoprolol: A systematic review and meta-analysis. Meloche, M., Khazaka, M., Kassem, I., Barhdadi, A., Dubé, M. P. and de Denus, S. . Br J Clin Pharmacol 2020. [BibTeX]
  • Study design of Dal-GenE, a pharmacogenetic trial targeting reduction of cardiovascular events with dalcetrapib. Tardif, J. C., Dubé, M. P., Pfeffer, M. A., Waters, D. D., Koenig, W., Maggioni, A. P., McMurray, J. J. V., Mooser, V., White, H. D., Heinonen, T., Black, D. M. and Guertin, M. C. . Am. Heart J. 2020: 157-165. [BibTeX]
  • Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study. Cadby, G., Melton, P. E., McCarthy, N. S., Giles, C., Mellett, N. A., Huynh, K., Hung, J., Beilby, J., Dubé, M. P., Watts, G. F., Blangero, J., Meikle, P. J. and Moses, E. K. . J. Lipid Res. 2020; 4: 537-545. [BibTeX]
  • Oral Anticoagulant Prescription Trends, Profile Use, and Determinants of Adherence in Patients with Atrial Fibrillation. Perreault, S., de Denus, S., White-Guay, B., Côté, R., Schnitzer, M. E., Dubé, M. P., Dorais, M. and Tardif, J. C. . Pharmacotherapy 2020; 1: 40-54. [BibTeX]
  • rs73185306 C/T Is Not a Predisposing Risk Factor for Inherited Chromosomally Integrated Human Herpesvirus 6A/B. Mouammine, A., Gravel, A., Dubuc, I., Feroz Zada, Y., Provost, S., Busseuil, D., Tardif, J. C., Dubé, M. P. and Flamand, L. . J. Infect. Dis. 2020; 6: 878-881. [BibTeX]

2019

  • Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction. Tardif, J. C., Kouz, S., Waters, D. D., Bertrand, O. F., Diaz, R., Maggioni, A. P., Pinto, F. J., Ibrahim, R., Gamra, H., Kiwan, G. S., Berry, C., López-Sendón, J., Ostadal, P., Koenig, W., Angoulvant, D., Grégoire, J. C., Lavoie, M. A., Dubé, M. P., Rhainds, D., Provencher, M., Blondeau, L., Orfanos, A., L'Allier, P. L., Guertin, M. C. and Roubille, F. . N. Engl. J. Med. 2019; 26: 2497-2505. [BibTeX]
  • Meta-analysis of Randomized Controlled Trials Assessing the Impact of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies on Mortality and Cardiovascular Outcomes. AlTurki, A., Marafi, M., Dawas, A., Dube, M. P., Vieira, L., Sherman, M. H., Gregoire, J., Thanassoulis, G., Tardif, J. C. and Huynh, T. . Am. J. Cardiol. 2019; 12: 1869-1875. [BibTeX]
  • Inherited Chromosomally Integrated Human Herpesvirus 6 Demonstrates Tissue-Specific RNA Expression In Vivo That Correlates with an Increased Antibody Immune Response. Peddu, V., Dubuc, I., Gravel, A., Xie, H., Huang, M. L., Tenenbaum, D., Jerome, K. R., Tardif, J. C., Dubé, M. P., Flamand, L. and Greninger, A. L. . J. Virol. 2019; 1. [BibTeX]
  • Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians. Wünnemann, F., Sin Lo, K., Langford-Avelar, A., Busseuil, D., Dubé, M. P., Tardif, J. C. and Lettre, G. . Circ Genom Precis Med 2019; 6: e002481. [BibTeX]
  • Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events. Patel, R. S., Schmidt, A. F., Tragante, V., McCubrey, R. O., Holmes, M. V., Howe, L. J., Direk, K., Åkerblom, A., Leander, K., Virani, S. S., Kaminski, K. A., Muehlschlegel, J. D., Dubé, M. P., Allayee, H., Almgren, P., Alver, M., Baranova, E. V., Behlouli, H., Boeckx, B., Braund, P. S., Breitling, L. P., Delgado, G., Duarte, N. E., Dufresne, L., Eriksson, N., Foco, L., Gijsberts, C. M., Gong, Y., Hartiala, J., Heydarpour, M. et al. Circ Genom Precis Med 2019; 4: e002471. [BibTeX]
  • Subsequent Event Risk in Individuals With Established Coronary Heart Disease. Patel, R. S., Tragante, V., Schmidt, A. F., McCubrey, R. O., Holmes, M. V., Howe, L. J., Direk, K., Åkerblom, A., Leander, K., Virani, S. S., Kaminski, K. A., Muehlschlegel, J. D., Allayee, H., Almgren, P., Alver, M., Baranova, E. V., Behloui, H., Boeckx, B., Braund, P. S., Breitling, L. P., Delgado, G., Duarte, N. E., Dubé, M. P., Dufresne, L., Eriksson, N., Foco, L., Scholz, M., Gijsberts, C. M., Glinge, C., Gong, Y. et al. Circ Genom Precis Med 2019; 4: e002470. [BibTeX]
  • Lipoprotein (a), arterial inflammation, and PCSK9 inhibition. Tardif, J. C., Rhéaume, E., Rhainds, D. and Dubé, M. P. . Eur. Heart J. 2019; 33: 2782-2784. [BibTeX]
  • Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A., Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G. et al. Nat. Genet. 2019; 3: 452-469. [BibTeX]
  • A Randomized, Double-blinded, Placebo-controlled Trial of Sitagliptin for Reducing Inflammation and Immune Activation in Treated and Suppressed Human Immunodeficiency Virus Infection. Dubé, M. P., Chan, E. S., Lake, J. E., Williams, B., Kinslow, J., Landay, A., Coombs, R. W., Floris-Moore, M., Ribaudo, H. J. and Yarasheski, K. E. . Clin. Infect. Dis. 2019; 7: 1165-1172. [BibTeX]
  • Nuclear receptor gene polymorphisms and warfarin dose requirements in the Quebec Warfarin Cohort. Shahabi, P., Lamothe, F., Dumas, S., Rouleau-Mailloux, É., Feroz Zada, Y., Provost, S., Asselin, G., Mongrain, I., Valois, D., Gaulin Marion, M. J., Lemieux Perreault, L. P., Perreault, S. and Dubé, M. P. . Pharmacogenomics J. 2019; 2: 147-156. [BibTeX]

2018

  • Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol. Low-Kam, C., Rhainds, D., Lo, K. S., Barhdadi, A., Boulé, M., Alem, S., Pedneault-Gagnon, V., Rhéaume, E., Dubé, M. P., Busseuil, D., Hegele, R. A., Lettre, G. and Tardif, J. C. . J Am Heart Assoc 2018; 16: e009545. [BibTeX]
  • Trajectories and Predictors of Longitudinal Preexposure Prophylaxis Adherence Among Men Who Have Sex With Men. Pasipanodya, E. C., Jain, S., Sun, X., Blumenthal, J., Ellorin, E., Corado, K., Dube, M. P., Daar, E. S., Morris, S. R. and Moore, D. J. . J. Infect. Dis. 2018; 10: 1551-1559. [BibTeX]
  • Pharmacogenetic content of commercial genome-wide genotyping arrays. Lemieux Perreault, L. P., Zaïd, N., Cameron, M., Mongrain, I. and Dubé, M. P. . Pharmacogenomics 2018; 15: 1159-1167. [BibTeX]
  • Biomarkers of dementia in obstructive sleep apnea. Baril, A. A., Carrier, J., Lafrenière, A., Warby, S., Poirier, J., Osorio, R. S., Ayas, N., Dubé, M. P., Petit, D. and Gosselin, N. . Sleep Med Rev 2018: 139-148. [BibTeX]
  • Randomized Clinical Trial Needed to Confirm Whether Dalcetrapib Improves Outcomes for Specific ADCY9 Genotype. Pfeffer, M. A., Dubé, M. P. and Tardif, J. C. . JAMA Cardiol 2018; 9: 897. [BibTeX]
  • Sex, drugs, and heart failure: a sex-sensitive review of the evidence base behind current heart failure clinical guidelines. Levinsson, A., Dubé, M. P., Tardif, J. C. and de Denus, S. . ESC Heart Fail 2018; 5: 745-754. [BibTeX]
  • Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A. Buscarlet, M., Provost, S., Zada, Y. F., Bourgoin, V., Mollica, L., Dubé, M. P. and Busque, L. . Blood 2018; 3: 277-280. [BibTeX]
  • Randomized Trial of a Health Coaching Intervention to Enhance Retention in Care: California Collaborative Treatment Group 594. Corado, K., Jain, S., Morris, S., Dube, M. P., Daar, E. S., He, F., Aldous, J. L., Sitapati, A., Haubrich, R., Milam, J. and Karris, M. Y. . AIDS Behav 2018; 8: 2698-2710. [BibTeX]
  • Pharmacogenomics of blood lipid regulation. Legault, M. A., Tardif, J. C. and Dubé, M. P. . Pharmacogenomics 2018; 7: 651-665. [BibTeX]
  • A prospective study of the impact of AGTR1 A1166C on the effects of candesartan in patients with heart failure. de Denus, S., Dubé, M. P., Fouodjio, R., Huynh, T., LeBlanc, M. H., Lepage, S., Sheppard, R., Giannetti, N., Lavoie, J., Mansour, A., Provost, S., Normand, V., Mongrain, I., Langlois, M., O'Meara, E., Ducharme, A., Racine, N., Guertin, M. C., Turgeon, J., Phillips, M. S., Rouleau, J. L., Tardif, J. C. and White, M. . Pharmacogenomics 2018; 7: 599-612. [BibTeX]
  • ADCY9 (Adenylate Cyclase Type 9) Inactivation Protects From Atherosclerosis Only in the Absence of CETP (Cholesteryl Ester Transfer Protein). Rautureau, Y., Deschambault, V., Higgins, M. È., Rivas, D., Mecteau, M., Geoffroy, P., Miquel, G., Uy, K., Sanchez, R., Lavoie, V., Brand, G., Nault, A., Williams, P. M., Suarez, M. L., Merlet, N., Lapointe, L., Duquette, N., Gillis, M. A., Samami, S., Mayer, G., Pouliot, P., Raignault, A., Maafi, F., Brodeur, M. R., Levesque, S., Guertin, M. C., Dubé, M. P., Thorin, É., Rhainds, D., Rhéaume, É. et al. Circulation 2018; 16: 1677-1692. [BibTeX]
  • A Discrete Event Simulation Model to Assess the Economic Value of a Hypothetical Pharmacogenomics Test for Statin-Induced Myopathy in Patients Initiating a Statin in Secondary Cardiovascular Prevention. Mitchell, D., Guertin, J. R., Dubois, A., Dubé, M. P., Tardif, J. C., Iliza, A. C., Fanton-Aita, F., Matteau, A. and LeLorier, J. . Mol Diagn Ther 2018; 2: 241-254. [BibTeX]
  • Rationale, design, and preliminary results of the Quebec Warfarin Cohort Study. Perreault, S., Shahabi, P., Côté, R., Dumas, S., Rouleau-Mailloux, É., Feroz Zada, Y., Provost, S., Mongrain, I., Dorais, M., Huynh, T., Kouz, S., Diaz, A., Blostein, M., de Denus, S., Turgeon, J., Ginsberg, J., Lelorier, J., Lalonde, L., Busque, L., Kassis, J., Talajic, M., Tardif, J. C. and Dubé, M. P. . Clin Cardiol 2018; 5: 576-585. [BibTeX]
  • Brief Report: Changes in Plasma RANKL-Osteoprotegerin in a Prospective, Randomized Clinical Trial of Initial Antiviral Therapy: A5260s. Kelesidis, T., Moser, C. B., Johnston, E., Stein, J. H., Dube, M. P., Yang, O. O., McComsey, G. A., Currier, J. S. and Brown, T. T. . J. Acquir. Immune Defic. Syndr. 2018; 3: 362-366. [BibTeX]
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Turcot, V., Lu, Y., Highland, H. M., Schurmann, C., Justice, A. E., Fine, R. S., Bradfield, J. P., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, A. E., Karaderi, T., Lempradl, A., Locke, A. E., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, K. L., Alfred, T., Feitosa, M. F., Masca, N. G. D., Manning, A. K., Medina-Gomez, C., Mudgal, P., Ng, M. C. Y., Reiner, A. P., Vedantam, S., Willems, S. M., Winkler, T. W. et al. Nat. Genet. 2018; 1: 26-41. [BibTeX]
  • Randomized Controlled Trial of Daily Text Messages to Support Adherence to Preexposure Prophylaxis in Individuals at Risk for Human Immunodeficiency Virus: The TAPIR Study. Moore, D. J., Jain, S., Dubé, M. P., Daar, E. S., Sun, X., Young, J., Corado, K., Ellorin, E., Milam, J., Collins, D., Blumenthal, J., Best, B. M., Anderson, P., Haubrich, R. and Morris, S. R. . Clin. Infect. Dis. 2018; 10: 1566-1572. [BibTeX]
  • Identification of the genetic determinants responsible for retinal degeneration in families of Mexican descent. Villanueva, A., Biswas, P., Kishaba, K., Suk, J., Tadimeti, K., Raghavendra, P. B., Nadeau, K., Lamontagne, B., Busque, L., Geoffroy, S., Mongrain, I., Asselin, G., Provost, S., Dubé, M. P., Nudleman, E. and Ayyagari, R. . Ophthalmic Genet. 2018; 1: 73-79. [BibTeX]
  • CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction. de Denus, S., Rouleau, J. L., Mann, D. L., Huggins, G. S., Pereira, N. L., Shah, S. H., Cappola, T. P., Fouodjio, R., Mongrain, I. and Dubé, M. P. . Pharmacogenomics J. 2018; 2: 232-237. [BibTeX]

2017

  • Exome-wide association study of plasma lipids in >300,000 individuals. Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Di Angelantonio, E., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C., Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I. et al. Nat. Genet. 2017; 12: 1758-1766. [BibTeX]
  • Pharmacogenetics of Lipid-Lowering Agents: an Update Review on Genotype-Dependent Effects of HDL-Targetingand Statin Therapies. Messas, N., Dubé, M. P. and Tardif, J. C. . Curr Atheroscler Rep 2017; 11: 43. [BibTeX]
  • ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels. Trigueros-Motos, L., van Capelleveen, J. C., Torta, F., Castaño, D., Zhang, L. H., Chai, E. C., Kang, M., Dimova, L. G., Schimmel, A. W. M., Tietjen, I., Radomski, C., Tan, L. J., Thiam, C. H., Narayanaswamy, P., Wu, D. H., Dorninger, F., Yakala, G. K., Barhdadi, A., Angeli, V., Dubé, M. P., Berger, J., Dallinga-Thie, G. M., Tietge, U. J. F., Wenk, M. R., Hayden, M. R., Hovingh, G. K. and Singaraja, R. R. . Arterioscler. Thromb. Vasc. Biol. 2017; 11: 2147-2155. [BibTeX]
  • Polygenic determinants in extremes of high-density lipoprotein cholesterol. Dron, J. S., Wang, J., Low-Kam, C., Khetarpal, S. A., Robinson, J. F., McIntyre, A. D., Ban, M. R., Cao, H., Rhainds, D., Dubé, M. P., Rader, D. J., Lettre, G., Tardif, J. C. and Hegele, R. A. . J. Lipid Res. 2017; 11: 2162-2170. [BibTeX]
  • CKing Precision in the Interpretation of Diagnostic Biomarkers. de Denus, S., Tardif, J. C. and Dubé, M. P. . Circ Cardiovasc Genet 2017; 4. [BibTeX]
  • DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions. Buscarlet, M., Provost, S., Zada, Y. F., Barhdadi, A., Bourgoin, V., Lépine, G., Mollica, L., Szuber, N., Dubé, M. P. and Busque, L. . Blood 2017; 6: 753-762. [BibTeX]
  • Diagnosis, Prevalence, Awareness, Treatment, Prevention, and Control of Hypertension in Cameroon: Protocol for a Systematic Review and Meta-Analysis of Clinic-Based and Community-Based Studies. Kuate Defo, B., Mbanya, J. C., Tardif, J. C., Ekundayo, O., Perreault, S., Potvin, L., Cote, R., Kengne, A. P., Choukem, S. P., Assah, F., Kingue, S., Richard, L., Pongou, R., Frohlich, K., Saji, J., Fournier, P., Sobngwi, E., Ridde, V., Dubé, M. P., De Denus, S., Mbacham, W., Lafrance, J. P., Nsagha, D. S., Mampuya, W., Dzudie, A., Cloutier, L., Zarowsky, C., Tanya, A., Ndom, P., Hatem, M. et al. JMIR Res Protoc 2017; 5: e102. [BibTeX]
  • Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve. Yang, B., Zhou, W., Jiao, J., Nielsen, J. B., Mathis, M. R., Heydarpour, M., Lettre, G., Folkersen, L., Prakash, S., Schurmann, C., Fritsche, L., Farnum, G. A., Lin, M., Othman, M., Hornsby, W., Driscoll, A., Levasseur, A., Thomas, M., Farhat, L., Dubé, M. P., Isselbacher, E. M., Franco-Cereceda, A., Guo, D. C., Bottinger, E. P., Deeb, G. M., Booher, A., Kheterpal, S., Chen, Y. E., Kang, H. M., Kitzman, J. et al. Nat Commun 2017: 15481. [BibTeX]
  • Methylomic changes in individuals with psychosis, prenatally exposed to endocrine disrupting compounds: Lessons from diethylstilbestrol. Rivollier, F., Chaumette, B., Bendjemaa, N., Chayet, M., Millet, B., Jaafari, N., Barhdadi, A., Lemieux Perreault, L. P., Provost, S., Dubé, M. P., Gaillard, R., Krebs, M. O. and Kebir, O. . PLoS ONE 2017; 4: e0174783. [BibTeX]
  • Practical Review of Recognition and Management of Obesity and Lipohypertrophy in Human Immunodeficiency Virus Infection. Lake, J. E., Stanley, T. L., Apovian, C. M., Bhasin, S., Brown, T. T., Capeau, J., Currier, J. S., Dube, M. P., Falutz, J., Grinspoon, S. K., Guaraldi, G., Martinez, E., McComsey, G. A., Sattler, F. R. and Erlandson, K. M. . Clin. Infect. Dis. 2017; 10: 1422-1429. [BibTeX]
  • Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., König, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E. E., Björkegren, J. L., Weeke, P. E., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., van Iperen, E. et al. J. Am. Coll. Cardiol. 2017; 7: 823-836. [BibTeX]
  • CETP: Pharmacogenomics-Based Response to the CETP Inhibitor Dalcetrapib. Tardif, J. C., Rhainds, D., Rhéaume, E. and Dubé, M. P. . Arterioscler. Thromb. Vasc. Biol. 2017; 3: 396-400. [BibTeX]
  • Older adults with heart failure treated with carvedilol, bisoprolol, or metoprolol tartrate: risk of mortality. Perreault, S., de Denus, S., White, M., White-Guay, B., Bouvier, M., Dorais, M., Dubé, M. P., Rouleau, J. L., Tardif, J. C., Jenna, S., Haibe-Kains, B., Leduc, R. and Deblois, D. . Pharmacoepidemiol Drug Saf 2017; 1: 81-90. [BibTeX]
  • Changes in plasma levels of oxidized lipoproteins and lipoprotein subfractions with atazanavir-, raltegravir-, darunavir-based initial antiviral therapy and associations with common carotid artery intima-media thickness: ACTG 5260s. Kelesidis, T., Tran, T. T. T., Brown, T. T., Moser, C., Ribaudo, H. J., Dube, M. P., Yang, O. O., McComsey, G. A., Stein, J. H. and Currier, J. S. . Antivir. Ther. (Lond.) 2017; 2: 113-126. [BibTeX]
  • Methylomic changes during conversion to psychosis. Kebir, O., Chaumette, B., Rivollier, F., Miozzo, F., Lemieux Perreault, L. P., Barhdadi, A., Provost, S., Plaze, M., Bourgin, J., Gaillard, R., Mezger, V., Dubé, M. P., Krebs, M. O., Mam-Lam-Fook, C., Alexandre, C., Magadu, E., Martinez, G., Kazes, M., Chayet, M., Gay, O. and Prost, Z. . Mol. Psychiatry 2017; 4: 512-518. [BibTeX]
  • A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials. de Denus, S., Rouleau, J. L., Mann, D. L., Huggins, G. S., Cappola, T. P., Shah, S. H., Keleti, J., Zada, Y. F., Provost, S., Bardhadi, A., Phillips, M. S., Normand, V., Mongrain, I. and Dubé, M. P. . Pharmacogenomics J. 2017; 2: 192-200. [BibTeX]

2016

  • Pharmacogenomic approaches to lipid-regulating trials. Bertrand, M. J., Dubé, M. P. and Tardif, J. C. . Curr. Opin. Lipidol. 2016; 6: 557-562. [BibTeX]
  • Polygenic Versus Monogenic Causes of Hypercholesterolemia Ascertained Clinically. Wang, J., Dron, J. S., Ban, M. R., Robinson, J. F., McIntyre, A. D., Alazzam, M., Zhao, P. J., Dilliott, A. A., Cao, H., Huff, M. W., Rhainds, D., Low-Kam, C., Dubé, M. P., Lettre, G., Tardif, J. C. and Hegele, R. A. . Arterioscler. Thromb. Vasc. Biol. 2016; 12: 2439-2445. [BibTeX]
  • Paternal Age Explains a Major Portion of De Novo Germline Mutation Rate Variability in Healthy Individuals. Girard, S. L., Bourassa, C. V., Lemieux Perreault, L. P., Legault, M. A., Barhdadi, A., Ambalavanan, A., Brendgen, M., Vitaro, F., Noreau, A., Dionne, G., Tremblay, R. E., Dion, P. A., Boivin, M., Dubé, M. P. and Rouleau, G. A. . PLoS ONE 2016; 10: e0164212. [BibTeX]
  • A model to assess the cost-effectiveness of pharmacogenomics tests in chronic heart failure: the case of ivabradine. Iliza, A. C., Matteau, A., Guertin, J. R., Mitchell, D., Fanton-Aita, F., Dubois, A., Dubé, M. P., Tardif, J. C. and LeLorier, J. . Pharmacogenomics 2016; 15: 1693-1706. [BibTeX]
  • Changes in Insulin Resistance After Initiation of Raltegravir or Protease Inhibitors With Tenofovir-Emtricitabine: AIDS Clinical Trials Group A5260s. Dirajlal-Fargo, S., Moser, C., Brown, T. T., Kelesidis, T., Dube, M. P., Stein, J. H., Currier, J. and McComsey, G. A. . Open Forum Infect Dis 2016; 3: ofw174. [BibTeX]
  • Maximal expected benefits from lowering cholesterol in primary prevention for a high-risk population. Fanton-Aita, F., Matteau, A., Iliza, A. C., Mitchell, D., Guertin, J. R., Dubois, A., Dubé, M. P., Tardif, J. C. and LeLorier, J. . Curr Med Res Opin 2016; 12: 1955-1958. [BibTeX]
  • Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Postmus, I., Warren, H. R., Trompet, S., Arsenault, B. J., Avery, C. L., Bis, J. C., Chasman, D. I., de Keyser, C. E., Deshmukh, H. A., Evans, D. S., Feng, Q., Li, X., Smit, R. A., Smith, A. V., Sun, F., Taylor, K. D., Arnold, A. M., Barnes, M. R., Barratt, B. J., Betteridge, J., Boekholdt, S. M., Boerwinkle, E., Buckley, B. M., Chen, Y. I., de Craen, A. J., Cummings, S. R., Denny, J. C., Dubé, M. P., Durrington, P. N., Eiriksdottir, G. et al. J. Med. Genet. 2016; 12: 835-845. [BibTeX]
  • genipe: an automated genome-wide imputation pipeline with automatic reporting and statistical tools. Lemieux Perreault, L. P., Legault, M. A., Asselin, G. and Dubé, M. P. . Bioinformatics 2016; 23: 3661-3663. [BibTeX]
  • Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation: Concordance With Clinical Outcomes. Tardif, J. C., Rhainds, D., Brodeur, M., Feroz Zada, Y., Fouodjio, R., Provost, S., Boulé, M., Alem, S., Grégoire, J. C., L'Allier, P. L., Ibrahim, R., Guertin, M. C., Mongrain, I., Olsson, A. G., Schwartz, G. G., Rhéaume, E. and Dubé, M. P. . Circ Cardiovasc Genet 2016; 4: 340-348. [BibTeX]
  • Whole-genome sequencing in French Canadians from Quebec. Low-Kam, C., Rhainds, D., Lo, K. S., Provost, S., Mongrain, I., Dubois, A., Perreault, S., Robinson, J. F., Hegele, R. A., Dubé, M. P., Tardif, J. C. and Lettre, G. . Hum. Genet. 2016; 11: 1213-1221. [BibTeX]
  • DNA methylation signature of human fetal alcohol spectrum disorder. Portales-Casamar, E., Lussier, A. A., Jones, M. J., MacIsaac, J. L., Edgar, R. D., Mah, S. M., Barhdadi, A., Provost, S., Lemieux-Perreault, L. P., Cynader, M. S., Chudley, A. E., Dubé, M. P., Reynolds, J. N., Pavlidis, P. and Kobor, M. S. . Epigenetics Chromatin 2016: 25. [BibTeX]
  • Changes in Markers of T-Cell Senescence and Exhaustion With Atazanavir-, Raltegravir-, and Darunavir-Based Initial Antiviral Therapy: ACTG 5260s. Kelesidis, T., Moser, C., Stein, J. H., Brown, T. T., Tran, T. T., Ribaudo, H. J., Dube, M. P., Yang, O. O., Currier, J. S. and McComsey, G. A. . J. Infect. Dis. 2016; 5: 748-752. [BibTeX]
  • Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. Eicher, J. D., Chami, N., Kacprowski, T., Nomura, A., Chen, M. H., Yanek, L. R., Tajuddin, S. M., Schick, U. M., Slater, A. J., Pankratz, N., Polfus, L., Schurmann, C., Giri, A., Brody, J. A., Lange, L. A., Manichaikul, A., Hill, W. D., Pazoki, R., Elliot, P., Evangelou, E., Tzoulaki, I., Gao, H., Vergnaud, A. C., Mathias, R. A., Becker, D. M., Becker, L. C., Burt, A., Crosslin, D. R., Lyytikäinen, L. P., Nikus, K. et al. Am. J. Hum. Genet. 2016; 1: 40-55. [BibTeX]
  • Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. Chami, N., Chen, M. H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D., Raffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L. C., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R. et al. Am. J. Hum. Genet. 2016; 1: 8-21. [BibTeX]
  • Pillbox Use and INR Stability in a Prospective Cohort of New Warfarin Users. Dumas, S., Rouleau-Mailloux, E., Bouchama, N., Lahcene, H., Talajic, M., Tardif, J. C., Gaulin, M. J., Provost, S., Dubé, M. P. and Perreault, S. . J Manag Care Spec Pharm 2016; 6: 676-684. [BibTeX]
  • An expanded pharmacogenomics warfarin dosing table with utility in generalised dosing guidance. Shahabi, P., Scheinfeldt, L. B., Lynch, D. E., Schmidlen, T. J., Perreault, S., Keller, M. A., Kasper, R., Wawak, L., Jarvis, J. P., Gerry, N. P., Gordon, E. S., Christman, M. F., Dubé, M. P. and Gharani, N. . Thromb. Haemost. 2016; 2: 337-348. [BibTeX]
  • Nucleoside-Sparing Regimens With Raltegravir and a Boosted Protease Inhibitor: An Unsettled Issue. Karris, M. Y., Jain, S., Bowman, V. Q., Rieg, G., Goicoechea, M., Dube, M. P., Kerkar, S., Kemper, C., Diamond, C., Sun, X., Daar, E. S., Haubrich, R. H. and Morris, S. . J. Acquir. Immune Defic. Syndr. 2016; 2: 48-50. [BibTeX]
  • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. Stitziel, N. O., Stirrups, K. E., Masca, N. G., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M. P., Goel, A., Farrall, M., Peloso, G. M., Won, H. H., Do, R., van Iperen, E., Kanoni, S., Kruppa, J., Mahajan, A., Scott, R. A., Willenberg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S., Donnelly, L. A., Asselta, R., Merlini, P. A. et al. N. Engl. J. Med. 2016; 12: 1134-1144. [BibTeX]
  • Avoidance of Vitamin K-Rich Foods Is Common among Warfarin Users and Translates into Lower Usual Vitamin K Intakes. Leblanc, C., Dubé, M. P., Presse, N., Dumas, S., Nguyen, M., Rouleau-Mailloux, É., Perreault, S. and Ferland, G. . J Acad Nutr Diet 2016; 6: 1000-1007. [BibTeX]
  • Testing the role of predicted gene knockouts in human anthropometric trait variation. Lessard, S., Manning, A. K., Low-Kam, C., Auer, P. L., Giri, A., Graff, M., Schurmann, C., Yaghootkar, H., Luan, J., Esko, T., Karaderi, T., Bottinger, E. P., Lu, Y., Carlson, C., Caulfield, M., Dubé, M. P., Jackson, R. D., Kooperberg, C., McKnight, B., Mongrain, I., Peters, U., Reiner, A. P., Rhainds, D., Sotoodehnia, N., Hirschhorn, J. N., Scott, R. A., Munroe, P. B., Frayling, T. M., Loos, R. J., North, K. E. et al. Hum. Mol. Genet. 2016; 10: 2082-2092. [BibTeX]
  • Body Composition Changes After Initiation of Raltegravir or Protease Inhibitors: ACTG A5260s. McComsey, G. A., Moser, C., Currier, J., Ribaudo, H. J., Paczuski, P., Dubé, M. P., Kelesidis, T., Rothenberg, J., Stein, J. H. and Brown, T. T. . Clin. Infect. Dis. 2016; 7: 853-862. [BibTeX]
  • Pharmacogenomics to Revive Drug Development in Cardiovascular Disease. Dubé, M. P., de Denus, S. and Tardif, J. C. . Cardiovasc Drugs Ther 2016; 1: 59-64. [BibTeX]
  • Resting heart rate as a predictor of aortic valve stenosis progression. de Oliveira Moraes, A. B., Stähli, B. E., Arsenault, B. J., Busseuil, D., Merlet, N., Gebhard, C., Fortier, A., Rhainds, D., Dubé, M. P., Guertin, M. C., Asgar, A., Rhéaume, E. and Tardif, J. C. . Int. J. Cardiol. 2016: 149-151. [BibTeX]
  • Impact of regular physical activity on weekly warfarin dose requirement. Rouleau-Mailloux, É., Shahabi, P., Dumas, S., Feroz Zada, Y., Provost, S., Hu, J., Nguyen, J., Bouchama, N., Mongrain, I., Talajic, M., Tardif, J. C., Perreault, S. and Dubé, M. P. . J. Thromb. Thrombolysis 2016; 2: 328-335. [BibTeX]

2015

  • Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease. Guauque-Olarte, S., Messika-Zeitoun, D., Droit, A., Lamontagne, M., Tremblay-Marchand, J., Lavoie-Charland, E., Gaudreault, N., Arsenault, B. J., Dubé, M. P., Tardif, J. C., Body, S. C., Seidman, J. G., Boileau, C., Mathieu, P., Pibarot, P. and Bossé, Y. . Circ Cardiovasc Genet 2015; 6: 812-822. [BibTeX]
  • A prospective, randomized clinical trial of antiretroviral therapies on carotid wall thickness. Stein, J. H., Ribaudo, H. J., Hodis, H. N., Brown, T. T., Tran, T. T., Yan, M., Brodell, E. L., Kelesidis, T., McComsey, G. A., Dube, M. P., Murphy, R. L. and Currier, J. S. . AIDS 2015; 14: 1775-1783. [BibTeX]
  • Will personalized drugs for cardiovascular disease become an option? - Defining 'Evidence-based personalized medicine' for its implementation and future use. de Denus, S., Dubé, M. P. and Tardif, J. C. . Expert Opin Pharmacother 2015; 17: 2549-2552. [BibTeX]
  • Mutation burden of rare variants in schizophrenia candidate genes. Girard, S. L., Dion, P. A., Bourassa, C. V., Geoffroy, S., Lachance-Touchette, P., Barhdadi, A., Langlois, M., Joober, R., Krebs, M. O., Dubé, M. P. and Rouleau, G. A. . PLoS ONE 2015; 6: e0128988. [BibTeX]
  • Genetic markers associated with cutaneous adverse drug reactions to allopurinol: a systematic review. Jarjour, S., Barrette, M., Normand, V., Rouleau, J. L., Dubé, M. P. and de Denus, S. . Pharmacogenomics 2015; 7: 755-767. [BibTeX]
  • Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir. Brown, T. T., Moser, C., Currier, J. S., Ribaudo, H. J., Rothenberg, J., Kelesidis, T., Yang, O., Dubé, M. P., Murphy, R. L., Stein, J. H. and McComsey, G. A. . J. Infect. Dis. 2015; 8: 1241-1249. [BibTeX]
  • Changes in Inflammation and Immune Activation With Atazanavir-, Raltegravir-, Darunavir-Based Initial Antiviral Therapy: ACTG 5260s. Kelesidis, T., Tran, T. T., Stein, J. H., Brown, T. T., Moser, C., Ribaudo, H. J., Dube, M. P., Murphy, R., Yang, O. O., Currier, J. S. and McComsey, G. A. . Clin. Infect. Dis. 2015; 4: 651-660. [BibTeX]
  • Cardiovascular pharmacogenomics; state of current knowledge and implementation in practice. Shahabi, P. and Dubé, M. P. . Int. J. Cardiol. 2015: 772-795. [BibTeX]
  • Comparison of sequencing based CNV discovery methods using monozygotic twin quartets. Legault, M. A., Girard, S., Lemieux Perreault, L. P., Rouleau, G. A. and Dubé, M. P. . PLoS ONE 2015; 3: e0122287. [BibTeX]
  • Pharmacogenomic determinants of the cardiovascular effects of dalcetrapib. Tardif, J. C., Rhéaume, E., Lemieux Perreault, L. P., Grégoire, J. C., Feroz Zada, Y., Asselin, G., Provost, S., Barhdadi, A., Rhainds, D., L'Allier, P. L., Ibrahim, R., Upmanyu, R., Niesor, E. J., Benghozi, R., Suchankova, G., Laghrissi-Thode, F., Guertin, M. C., Olsson, A. G., Mongrain, I., Schwartz, G. G. and Dubé, M. P. . Circ Cardiovasc Genet 2015; 2: 372-382. [BibTeX]

2014

  • Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Postmus, I., Trompet, S., Deshmukh, H. A., Barnes, M. R., Li, X., Warren, H. R., Chasman, D. I., Zhou, K., Arsenault, B. J., Donnelly, L. A., Wiggins, K. L., Avery, C. L., Griffin, P., Feng, Q., Taylor, K. D., Li, G., Evans, D. S., Smith, A. V., de Keyser, C. E., Johnson, A. D., de Craen, A. J., Stott, D. J., Buckley, B. M., Ford, I., Westendorp, R. G., Slagboom, P. E., Sattar, N., Munroe, P. B., Sever, P., Poulter, N. et al. Nat Commun 2014: 5068. [BibTeX]
  • CKM and LILRB5 are associated with serum levels of creatine kinase. Dubé, M. P., Zetler, R., Barhdadi, A., Brown, A. M., Mongrain, I., Normand, V., Laplante, N., Asselin, G., Zada, Y. F., Provost, S., Bergeron, J., Kouz, S., Dufour, R., Diaz, A., de Denus, S., Turgeon, J., Rhéaume, E., Phillips, M. S. and Tardif, J. C. . Circ Cardiovasc Genet 2014; 6: 880-886. [BibTeX]
  • Genetic markers of cisplatin-induced hearing loss in children. Carleton, B. C., Ross, C. J., Pussegoda, K., Bhavsar, A. P., Visscher, H., Lee, J. W., Brooks, B., Rassekh, S. R., Dubé, M. P. and Hayden, M. R. . Clin. Pharmacol. Ther. 2014; 3: 296-298. [BibTeX]
  • Development of a broad-based ADME panel for use in pharmacogenomic studies. Brown, A. M., Renaud, Y., Ross, C., Hansen, M., Mongrain, I., Valois, D., Carleton, B. C., Hayden, M. R., Dubé, M. P., Tardif, J. C. and Phillips, M. S. . Pharmacogenomics 2014; 9: 1185-1195. [BibTeX]
  • Modifiers of (CAG)(n) instability in Machado-Joseph disease (MJD/SCA3) transmissions: an association study with DNA replication, repair and recombination genes. Martins, S., Pearson, C. E., Coutinho, P., Provost, S., Amorim, A., Dubé, M. P., Sequeiros, J. and Rouleau, G. A. . Hum. Genet. 2014; 10: 1311-1318. [BibTeX]
  • Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits. Auer, P. L., Teumer, A., Schick, U., O'Shaughnessy, A., Lo, K. S., Chami, N., Carlson, C., de Denus, S., Dubé, M. P., Haessler, J., Jackson, R. D., Kooperberg, C., Perreault, L. P., Nauck, M., Peters, U., Rioux, J. D., Schmidt, F., Turcot, V., Völker, U., Völzke, H., Greinacher, A., Hsu, L., Tardif, J. C., Diaz, G. A., Reiner, A. P. and Lettre, G. . Nat. Genet. 2014; 6: 629-634. [BibTeX]
  • Lipoprotein(a) levels, genotype, and incident aortic valve stenosis: a prospective Mendelian randomization study and replication in a case-control cohort. Arsenault, B. J., Boekholdt, S. M., Dubé, M. P., Rhéaume, E., Wareham, N. J., Khaw, K. T., Sandhu, M. S. and Tardif, J. C. . Circ Cardiovasc Genet 2014; 3: 304-310. [BibTeX]
  • Novel presenilin mutations within Moroccan patients with Early-Onset Alzheimer's Disease. El Kadmiri, N., Zaid, N., Zaid, Y., Tadevosyan, A., Hachem, A., Dubé, M. P., Hamzi, K., El Moutawakil, B., Slassi, I. and Nadifi, S. . Neuroscience 2014: 215-222. [BibTeX]
  • Novel mutations in the amyloid precursor protein gene within Moroccan patients with Alzheimer's disease. El Kadmiri, N., Zaid, N., Hachem, A., Zaid, Y., Dubé, M. P., Hamzi, K., El Moutawakil, B., Slassi, I. and Nadifi, S. . J. Mol. Neurosci. 2014; 2: 189-195. [BibTeX]
  • Comparison of genotype clustering tools with rare variants. Perreault, L. P., Legault, M. A., Barhdadi, A., Provost, S., Normand, V., Tardif, J. C. and Dubé, M. P. . BMC Bioinformatics 2014: 52. [BibTeX]
  • Cuckoo search epistasis: a new method for exploring significant genetic interactions. Aflakparast, M., Salimi, H., Gerami, A., Dubé, M. P., Visweswaran, S. and Masoudi-Nejad, A. . Heredity (Edinb) 2014; 6: 666-674. [BibTeX]
  • Validation of patient-reported warfarin dose in a prospective incident cohort study. Dumas, S., Rouleau-Mailloux, E., Barhdadi, A., Talajic, M., Tardif, J. C., Dubé, M. P. and Perreault, S. . Pharmacoepidemiol Drug Saf 2014; 3: 285-289. [BibTeX]
  • Evaluation of links between high-density lipoprotein genetics, functionality, and aortic valve stenosis risk in humans. Arsenault, B. J., Dubé, M. P., Brodeur, M. R., de Oliveira Moraes, A. B., Lavoie, V., Kernaleguen, A. E., Guauque-Olarte, S., Mathieu, P., Pibarot, P., Messika-Zeitoun, D., Bossé, Y., Rhainds, D., Rhéaume, E. and Tardif, J. C. . Arterioscler. Thromb. Vasc. Biol. 2014; 2: 457-462. [BibTeX]
  • Role of TPMT and COMT genetic variation in cisplatin-induced ototoxicity. Carleton, B. C., Ross, C. J., Bhavsar, A. P., Amstutz, U., Pussegoda, K., Visscher, H., Lee, J. W., Brooks, B., Rassekh, S. R., Dubé, M. P. and Hayden, M. R. . Clin. Pharmacol. Ther. 2014; 3: 253. [BibTeX]
  • Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent. Aminkeng, F., Ross, C. J., Rassekh, S. R., Brunham, L. R., Sistonen, J., Dube, M. P., Ibrahim, M., Nyambo, T. B., Omar, S. A., Froment, A., Bodo, J. M., Tishkoff, S., Carleton, B. C., Hayden, M. R., Hayden, M., Carleton, B., Ross, C., MacLeod, S., Wasserman, W., Mitton, C., Smith, A., Hildebrand, C., Castro Pastrana, L., Ghannadan, R., Rassekh, R., Lim, J., Miao, F., Visscher, H., Pussegoda, K., Aminkeng, F. et al. Pharmacogenomics J. 2014; 2: 160-170. [BibTeX]

2013

  • Effects of switching from efavirenz to raltegravir on endothelial function, bone mineral metabolism, inflammation, and renal function: a randomized, controlled trial. Gupta, S. K., Mi, D., Moe, S. M., Dubé, M. P. and Liu, Z. . J. Acquir. Immune Defic. Syndr. 2013; 3: 279-283. [BibTeX]
  • Low baseline CD4+ count is associated with greater bone mineral density loss after antiretroviral therapy initiation. Grant, P. M., Kitch, D., McComsey, G. A., Dube, M. P., Haubrich, R., Huang, J., Riddler, S., Tebas, P., Zolopa, A. R., Collier, A. C. and Brown, T. T. . Clin. Infect. Dis. 2013; 10: 1483-1488. [BibTeX]
  • pyGenClean: efficient tool for genetic data clean up before association testing. Lemieux Perreault, L. P., Provost, S., Legault, M. A., Barhdadi, A. and Dubé, M. P. . Bioinformatics 2013; 13: 1704-1705. [BibTeX]
  • Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children. Pussegoda, K., Ross, C. J., Visscher, H., Yazdanpanah, M., Brooks, B., Rassekh, S. R., Zada, Y. F., Dubé, M. P., Carleton, B. C., Hayden, M. R., Hayden, M., Carleton, B., Ross, C., MacLeod, S., Brooks, B., Smith, A., Hildebrand, C., Ghannadan, R., Rassekh, R., Miao, F., Visscher, H., Pussegoda, K., Higginson, M., Yazdanpanah, M., Nijssen-Jordan, C., Johnson, D., Verbeek, L., Kaczowka, R., Stevenson, P., Hurton, A. et al. Clin. Pharmacol. Ther. 2013; 2: 243-251. [BibTeX]
  • Institutional profile: the Beaulieu-Saucier Université de Montréal Pharmacogenomics Centre at the Montreal Heart Institute. Dubé, M. P. and Tardif, J. C. . Pharmacogenomics 2013; 2: 131-136. [BibTeX]
  • The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans. Singaraja, R. R., Sivapalaratnam, S., Hovingh, K., Dubé, M. P., Castro-Perez, J., Collins, H. L., Adelman, S. J., Riwanto, M., Manz, J., Hubbard, B., Tietjen, I., Wong, K., Mitnaul, L. J., van Heek, M., Lin, L., Roddy, T. A., McEwen, J., Dallinge-Thie, G., van Vark-van der Zee, L., Verwoert, G., Winther, M., van Duijn, C., Hofman, A., Trip, M. D., Marais, A. D., Asztalos, B., Landmesser, U., Sijbrands, E., Kastelein, J. J. and Hayden, M. R. . Circ Cardiovasc Genet 2013; 1: 54-62. [BibTeX]
  • Characterization of two novel cold-inducible K3 dehydrin genes from alfalfa (Medicago sativa spp. sativa L.). Dubé, M. P., Castonguay, Y., Cloutier, J., Michaud, J. and Bertrand, A. . Theor. Appl. Genet. 2013; 3: 823-835. [BibTeX]
  • Risk of congenital heart defects is influenced by genetic variation in folate metabolism. Christensen, K. E., Zada, Y. F., Rohlicek, C. V., Andelfinger, G. U., Michaud, J. L., Bigras, J. L., Richter, A., Dubé, M. P. and Rozen, R. . Cardiol Young 2013; 1: 89-98. [BibTeX]
  • Molecular physiology and breeding at the crossroads of cold hardiness improvement. Castonguay, Y., Dubé, M. P., Cloutier, J., Bertrand, A., Michaud, R. and Laberge, S. . Physiol Plant 2013; 1: 64-74. [BibTeX]

2012

  • Worsening endothelial function with efavirenz compared to protease inhibitors: a 12-month prospective study. Gupta, S. K., Shen, C., Moe, S. M., Kamendulis, L. M., Goldman, M. and Dubé, M. P. . PLoS ONE 2012; 9: e45716. [BibTeX]
  • Rare copy number variants contribute to congenital left-sided heart disease. Hitz, M. P., Lemieux-Perreault, L. P., Marshall, C., Feroz-Zada, Y., Davies, R., Yang, S. W., Lionel, A. C., D'Amours, G., Lemyre, E., Cullum, R., Bigras, J. L., Thibeault, M., Chetaille, P., Montpetit, A., Khairy, P., Overduin, B., Klaassen, S., Hoodless, P., Awadalla, P., Hussin, J., Idaghdour, Y., Nemer, M., Stewart, A. F., Boerkoel, C., Scherer, S. W., Richter, A., Dubé, M. P. and Andelfinger, G. . PLoS Genet. 2012; 9: e1002903. [BibTeX]
  • Segregation of LIPG, CETP, and GALNT2 mutations in Caucasian families with extremely high HDL cholesterol. Tietjen, I., Hovingh, G. K., Singaraja, R. R., Radomski, C., Barhdadi, A., McEwen, J., Chan, E., Mattice, M., Legendre, A., Franchini, P. L., Dubé, M. P., Kastelein, J. J. and Hayden, M. R. . PLoS ONE 2012; 8: e37437. [BibTeX]
  • Pooled DNA resequencing of 68 myocardial infarction candidate genes in French canadians. Beaudoin, M., Lo, K. S., N'Diaye, A., Rivas, M. A., Dubé, M. P., Laplante, N., Phillips, M. S., Rioux, J. D., Tardif, J. C. and Lettre, G. . Circ Cardiovasc Genet 2012; 5: 547-554. [BibTeX]
  • Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice. Wiltshire, S. A., Diez, E., Miao, Q., Dubé, M. P., Gagné, M., Paquette, O., Lafrenière, R. G., Ndao, M., Castellani, L. W., Skamene, E., Vidal, S. M. and Fortin, A. . Physiol. Genomics 2012; 17: 843-852. [BibTeX]
  • Tacrolimus-induced nephrotoxicity and genetic variability: a review. Gijsen, V. M., Madadi, P., Dube, M. P., Hesselink, D. A., Koren, G. and de Wildt, S. N. . Ann. Transplant. 2012; 2: 111-121. [BibTeX]
  • A novel PLP1 mutation further expands the clinical heterogeneity at the locus. Hand, C. K., Bernard, G., Dubé, M. P., Shevell, M. I. and Rouleau, G. A. . Can J Neurol Sci 2012; 2: 220-224. [BibTeX]
  • PRKCB is associated with calcineurin inhibitor-induced renal dysfunction in heart transplant recipients. Lachance, K., Barhdadi, A., Mongrain, I., Normand, V., Zakrzewski, M., Leblanc, M. H., Racine, N., Carrier, M., Ducharme, A., Turgeon, J., Dubé, M. P., Phillips, M. S., White, M. and de Denus, S. . Pharmacogenet. Genomics 2012; 5: 336-343. [BibTeX]
  • Validation of warfarin pharmacogenetic algorithms in clinical practice. Marin-Leblanc, M., Perreault, S., Bahroun, I., Lapointe, M., Mongrain, I., Provost, S., Turgeon, J., Talajic, M., Brugada, R., Phillips, M., Tardif, J. C. and Dubé, M. P. . Pharmacogenomics 2012; 1: 21-29. [BibTeX]
  • Intron-length polymorphism identifies a Y2K4 dehydrin variant linked to superior freezing tolerance in alfalfa. Castonguay, Y., Dubé, M. P., Cloutier, J., Michaud, R., Bertrand, A. and Laberge, S. . Theor. Appl. Genet. 2012; 5: 809-819. [BibTeX]
  • Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children. Visscher, H., Ross, C. J., Rassekh, S. R., Barhdadi, A., Dubé, M. P., Al-Saloos, H., Sandor, G. S., Caron, H. N., van Dalen, E. C., Kremer, L. C., van der Pal, H. J., Brown, A. M., Rogers, P. C., Phillips, M. S., Rieder, M. J., Carleton, B. C., Hayden, M. R., Visscher, H., Ross, C. J., Rassekh, S., Dube, M. P., Sandor, G. S., Rogers, P. C., Phillips, M. S., Rieder, M. J., Carleton, B. C., Hayden, M. R., Rassekh, S., Caron, H. N., van Dalen, E. C. et al. J. Clin. Oncol. 2012; 13: 1422-1428. [BibTeX]

2011

  • Mutations in a novel serine protease PRSS56 in families with nanophthalmos. Orr, A., Dubé, M. P., Zenteno, J. C., Jiang, H., Asselin, G., Evans, S. C., Caqueret, A., Lakosha, H., Letourneau, L., Marcadier, J., Matsuoka, M., Macgillivray, C., Nightingale, M., Papillon-Cavanagh, S., Perry, S., Provost, S., Ludman, M., Guernsey, D. L. and Samuels, M. E. . Mol. Vis. 2011: 1850-1861. [BibTeX]
  • Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec. Dubé, M. P., Bigras, J. L., Thibeault, M., Bureau, N., Chetaille, P., Richter, A., Mercier, J., Bellavance, M., Rohlicek, C., Rozen, R., Nemer, M., Khairy, P., Gendron, R. and Andelfinger, G. . Cardiol Young 2011; 6: 654-664. [BibTeX]
  • Fetal alcohol spectrum disorders: gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes. Reynolds, J. N., Weinberg, J., Clarren, S., Beaulieu, C., Rasmussen, C., Kobor, M., Dube, M. P. and Goldowitz, D. . Semin Pediatr Neurol 2011; 1: 49-55. [BibTeX]
  • Familial ventricular aneurysms and septal defects map to chromosome 10p15. Tremblay, N., Yang, S. W., Hitz, M. P., Asselin, G., Ginns, J., Riopel, K., Gendron, R., Montpetit, A., Duhig, E., Dubé, M. P., Radford, D. and Andelfinger, G. . Eur. Heart J. 2011; 5: 568-573. [BibTeX]
  • Association between renal function and CYP3A5 genotype in heart transplant recipients treated with calcineurin inhibitors. de Denus, S., Zakrzewski, M., Barhdadi, A., Leblanc, M. H., Racine, N., Bélanger, F., Carrier, M., Ducharme, A., Dubé, M. P., Turgeon, J. and White, M. . J. Heart Lung Transplant. 2011; 3: 326-331. [BibTeX]

2010

  • A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura. Lafrenière, R. G., Cader, M. Z., Poulin, J. F., Andres-Enguix, I., Simoneau, M., Gupta, N., Boisvert, K., Lafrenière, F., McLaughlan, S., Dubé, M. P., Marcinkiewicz, M. M., Ramagopalan, S., Ansorge, O., Brais, B., Sequeiros, J., Pereira-Monteiro, J. M., Griffiths, L. R., Tucker, S. J., Ebers, G. and Rouleau, G. A. . Nat. Med. 2010; 10: 1157-1160. [BibTeX]
  • Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. Awadalla, P., Gauthier, J., Myers, R. A., Casals, F., Hamdan, F. F., Griffing, A. R., Côté, M., Henrion, E., Spiegelman, D., Tarabeux, J., Piton, A., Yang, Y., Boyko, A., Bustamante, C., Xiong, L., Rapoport, J. L., Addington, A. M., DeLisi, J. L., Krebs, M. O., Joober, R., Millet, B., Fombonne, E., Mottron, L., Zilversmit, M., Keebler, J., Daoud, H., Marineau, C., Roy-Gagnon, M. H., Dubé, M. P., Eyre-Walker, A. et al. Am. J. Hum. Genet. 2010; 3: 316-324. [BibTeX]
  • Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1. Fortin, A., Diez, E., Ritchie, J., Sotocinal, S. G., Dube, M. P., Gagne, M., Paquette, O., Skamene, E. and Mogil, J. S. . Genes Brain Behav. 2010; 8: 856-867. [BibTeX]
  • Genetic determinants of blood pressure reduction following potassium supplementation: and the candidates are... de Denus, S. and Dubé, M. P. . J. Hypertens. 2010; 4: 668-670. [BibTeX]
  • Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases. Xiong, L., Montplaisir, J., Desautels, A., Barhdadi, A., Turecki, G., Levchenko, A., Thibodeau, P., Dubé, M. P., Gaspar, C. and Rouleau, G. A. . Arch. Neurol. 2010; 5: 617-622. [BibTeX]
  • Partitioning of copy-number genotypes in pedigrees. Perreault, L. P., Andelfinger, G. U., Asselin, G. and Dubé, M. P. . BMC Bioinformatics 2010: 226. [BibTeX]
  • Mutations in DCC cause congenital mirror movements. Srour, M., Rivière, J. B., Pham, J. M., Dubé, M. P., Girard, S., Morin, S., Dion, P. A., Asselin, G., Rochefort, D., Hince, P., Diab, S., Sharafaddinzadeh, N., Chouinard, S., Théoret, H., Charron, F. and Rouleau, G. A. . Science 2010; 5978: 592. [BibTeX]
  • De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Gauthier, J., Champagne, N., Lafrenière, R. G., Xiong, L., Spiegelman, D., Brustein, E., Lapointe, M., Peng, H., Côté, M., Noreau, A., Hamdan, F. F., Addington, A. M., Rapoport, J. L., Delisi, L. E., Krebs, M. O., Joober, R., Fathalli, F., Mouaffak, F., Haghighi, A. P., Néri, C., Dubé, M. P., Samuels, M. E., Marineau, C., Stone, E. A., Awadalla, P., Barker, P. A., Carbonetto, S., Drapeau, P., Rouleau, G. A., Daignault, K. et al. Proc. Natl. Acad. Sci. U.S.A. 2010; 17: 7863-7868. [BibTeX]
  • Testing for gene-gene interaction with AMMI models. Barhdadi, A. and Dubé, M. P. . Stat Appl Genet Mol Biol 2010: Article 2. [BibTeX]
  • Genome-wide TDT analysis in French-Canadian families with Tourette syndrome. Rivière, J. B., St-Onge, J., Gaspar, C., Diab, S., Dion, Y., Lespérance, P., Tellier, G., Richer, F., Chouinard, S., Dubé, M. P., Rouleau, G. A., Charest, M., Chau, V., Desbeaumes, V., Dion, M. H., Duplessis, M., Girard, C., Handanos, D., Jodoin, N., Assouad, D. J., Lemay, M., Ng, A., Srour, M., Thibault, M., Tremblay, I. and Vézina, M. . Can J Neurol Sci 2010; 1: 110-112. [BibTeX]
  • Genetics of bronchopulmonary dysplasia in the age of genomics. Lavoie, P. M. and Dubé, M. P. . Curr. Opin. Pediatr. 2010; 2: 134-138. [BibTeX]
  • Change to atazanavir/ritonavir treatment improves lipids but not endothelial function in patients on stable antiretroviral therapy. Murphy, R. L., Berzins, B., Zala, C., Fichtenbaum, C., Dube, M. P., Guaraldi, G., Torriani, F., Belsey, E., Mitchell, C. and Stein, J. H. . AIDS 2010; 6: 885-890. [BibTeX]
  • Novel mutations in the sacsin gene in ataxia patients from Maritime Canada. Guernsey, D. L., Dubé, M. P., Jiang, H., Asselin, G., Blowers, S., Evans, S., Ferguson, M., Macgillivray, C., Matsuoka, M., Nightingale, M., Rideout, A., Delatycki, M., Orr, A., Ludman, M., Dooley, J., Riddell, C. and Samuels, M. E. . J. Neurol. Sci. 2010; 1-2: 79-87. [BibTeX]

2009

  • Different models and single-nucleotide polymorphisms signal the simulated weak gene-gene interaction for a quantitative trait using haplotype-based and mixed models testing. Kovac, I. P. and Dubé, M. P. . BMC Proc 2009: S77. [BibTeX]
  • The challenge of detecting epistasis (G x G interactions): Genetic Analysis Workshop 16. An, P., Mukherjee, O., Chanda, P., Yao, L., Engelman, C. D., Huang, C. H., Zheng, T., Kovac, I. P., Dubé, M. P., Liang, X., Li, J., de Andrade, M., Culverhouse, R., Malzahn, D., Manning, A. K., Clarke, G. M., Jung, J. and Province, M. A. . Genet. Epidemiol. 2009: 58-67. [BibTeX]
  • Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Ross, C. J., Katzov-Eckert, H., Dubé, M. P., Brooks, B., Rassekh, S. R., Barhdadi, A., Feroz-Zada, Y., Visscher, H., Brown, A. M., Rieder, M. J., Rogers, P. C., Phillips, M. S., Carleton, B. C., Hayden, M. R., Hayden, M., Carleton, B., Ross, C., Smith, A., MacLeod, S., Wasserman, W., Hildebrand, C., Castro, L., Ghannadan, R., Carter, C., Honeyman, G., Katzov, H., Rassekh, R., Lau, L., Lim, J., Miao, F. et al. Nat. Genet. 2009; 12: 1345-1349. [BibTeX]
  • Association between cervical and intracranial dimensions and syringomyelia in the cavalier King Charles spaniel. Carruthers, H., Rusbridge, C., Dubé, M. P., Holmes, M. and Jeffery, N. . J Small Anim Pract 2009; 8: 394-398. [BibTeX]
  • Application of principal component analysis to pharmacogenomic studies in Canada. Visscher, H., Ross, C. J., Dubé, M. P., Brown, A. M., Phillips, M. S., Carleton, B. C. and Hayden, M. R. . Pharmacogenomics J. 2009; 6: 362-372. [BibTeX]
  • Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2. Guernsey, D. L., Jiang, H., Evans, S. C., Ferguson, M., Matsuoka, M., Nightingale, M., Rideout, A. L., Provost, S., Bedard, K., Orr, A., Dubé, M. P., Ludman, M. and Samuels, M. E. . Am. J. Hum. Genet. 2009; 1: 120-129. [BibTeX]
  • Genetic modulation of brugada syndrome by a common polymorphism. Lizotte, E., Junttila, M. J., Dube, M. P., Hong, K., Benito, B., DE Zutter, M., Henkens, S., Sarkozy, A., Huikuri, H. V., Towbin, J., Vatta, M., Brugada, P., Brugada, J. and Brugada, R. . J. Cardiovasc. Electrophysiol. 2009; 10: 1137-1141. [BibTeX]
  • Application of homozygosity haplotype analysis to genetic mapping with high-density SNP genotype data. Jiang, H., Orr, A., Guernsey, D. L., Robitaille, J., Asselin, G., Samuels, M. E. and Dubé, M. P. . PLoS ONE 2009; 4: e5280. [BibTeX]
  • Autosomal-dominant locus for Restless Legs Syndrome in French-Canadians on chromosome 16p12.1. Levchenko, A., Montplaisir, J. Y., Asselin, G., Provost, S., Girard, S. L., Xiong, L., Lemyre, E., St-Onge, J., Thibodeau, P., Desautels, A., Turecki, G., Gaspar, C., Dubé, M. P. and Rouleau, G. A. . Mov. Disord. 2009; 1: 40-50. [BibTeX]
  • Genetic predictors of depressive symptoms in cardiac patients. McCaffery, J. M., Duan, Q. L., Frasure-Smith, N., Barhdadi, A., Lespérance, F., Théroux, P., Rouleau, G. A. and Dubé, M. P. . Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009; 3: 381-388. [BibTeX]

2008

  • Génome Québec & Montreal Heart Institute Pharmacogenomics Centre: a translational pharmacogenomics platform--from R&D to the clinic. Phillips, M. S., Hihi, A. K., van Rooij, T., Smith, A. C., James, S., Marsh, S., Laplante, N., Dubé, M. P. and Tardif, J. C. . Pharmacogenomics 2008; 10: 1391-1396. [BibTeX]
  • Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Piton, A., Michaud, J. L., Peng, H., Aradhya, S., Gauthier, J., Mottron, L., Champagne, N., Lafrenière, R. G., Hamdan, F. F., Joober, R., Fombonne, E., Marineau, C., Cossette, P., Dubé, M. P., Haghighi, P., Drapeau, P., Barker, P. A., Carbonetto, S., Rouleau, G. A., Yang, Y., Laurent, S., Noreau, A., Henrion, E., Spiegelman, D., Diallo, O., Destroismaisons, L., Duguay, J., Kuku, F., Karemera, L., Côté, M. et al. Hum. Mol. Genet. 2008; 24: 3965-3974. [BibTeX]
  • Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s. Torriani, F. J., Komarow, L., Parker, R. A., Cotter, B. R., Currier, J. S., Dubé, M. P., Fichtenbaum, C. J., Gerschenson, M., Mitchell, C. K., Murphy, R. L., Squires, K. and Stein, J. H. . J. Am. Coll. Cardiol. 2008; 7: 569-576. [BibTeX]
  • Effects of AGTR1 A1166C gene polymorphism in patients with heart failure treated with candesartan. de Denus, S., Zakrzewski-Jakubiak, M., Dubé, M. P., Bélanger, F., Lepage, S., Leblanc, M. H., Gossard, D., Ducharme, A., Racine, N., Whittom, L., Lavoie, J., Touyz, R. M., Turgeon, J. and White, M. . Ann Pharmacother 2008; 7: 925-932. [BibTeX]
  • Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure. Zakrzewski-Jakubiak, M., de Denus, S., Dubé, M. P., Bélanger, F., White, M. and Turgeon, J. . Br J Clin Pharmacol 2008; 5: 742-751. [BibTeX]
  • A novel locus for idiopathic generalized epilepsy in French-Canadian families maps to 10p11. Kinirons, P., Verlaan, D. J., Dubé, M. P., Poirier, J., Deacon, C., Lortie, A., Clément, J. F., Desbiens, R., Carmant, L., Cieuta-Walti, C., Shevell, M., Rouleau, G. A. and Cossette, P. . Am. J. Med. Genet. A 2008; 5: 578-584. [BibTeX]
  • No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans. Bolduc, V., Chagnon, P., Provost, S., Dubé, M. P., Belisle, C., Gingras, M., Mollica, L. and Busque, L. . J. Clin. Invest. 2008; 1: 333-341. [BibTeX]

2007

  • Two-stage strategies to detect gene x gene interactions in case-control data. Barhdadi, A. and Dubé, M. P. . BMC Proc 2007: S135. [BibTeX]
  • Multistage designs in the genomic era: providing balance in complex disease studies. Dubé, M. P., Schmidt, S., Hauser, E., Darabi, H., Li, J., Barhdadi, A., Wang, X., Sha, Q., Zhang, Z., Wang, T., Aschard, H., Guedj, M., Rohlfs, R., Anderson, A., Taylor, C., Mirea, L., Nickolov, R., Milanov, V., Yang, H. C., Song, Y. and Sinha, R. . Genet. Epidemiol. 2007: S118-123. [BibTeX]
  • The genetics of congenital amusia (tone deafness): a family-aggregation study. Peretz, I., Cummings, S. and Dubé, M. P. . Am. J. Hum. Genet. 2007; 3: 582-588. [BibTeX]
  • Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. Orr, A., Dubé, M. P., Marcadier, J., Jiang, H., Federico, A., George, S., Seamone, C., Andrews, D., Dubord, P., Holland, S., Provost, S., Mongrain, V., Evans, S., Higgins, B., Bowman, S., Guernsey, D. and Samuels, M. . PLoS ONE 2007; 8: e685. [BibTeX]
  • Syringomyelia in cavalier King Charles spaniels: the relationship between syrinx dimensions and pain. Rusbridge, C., Carruthers, H., Dubé, M. P., Holmes, M. and Jeffery, N. D. . J Small Anim Pract 2007; 8: 432-436. [BibTeX]
  • Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384. Dubé, M. P., Komarow, L., Mulligan, K., Grinspoon, S. K., Parker, R. A., Robbins, G. K., Roubenoff, R. and Tebas, P. . J. Acquir. Immune Defic. Syndr. 2007; 5: 508-514. [BibTeX]
  • Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384. Dubé, M. P., Parker, R. A., Mulligan, K., Tebas, P., Robbins, G. K., Roubenoff, R. and Grinspoon, S. K. . Clin. Infect. Dis. 2007; 1: 120-126. [BibTeX]
  • Molecular genetic studies of DMT1 on 12q in French-Canadian restless legs syndrome patients and families. Xiong, L., Dion, P., Montplaisir, J., Levchenko, A., Thibodeau, P., Karemera, L., Rivière, J. B., St-Onge, J., Gaspar, C., Dubé, M. P., Desautels, A., Turecki, G. and Rouleau, G. A. . Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007; 7: 911-917. [BibTeX]
  • Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations. Goldberg, Y. P., MacFarlane, J., MacDonald, M. L., Thompson, J., Dube, M. P., Mattice, M., Fraser, R., Young, C., Hossain, S., Pape, T., Payne, B., Radomski, C., Donaldson, G., Ives, E., Cox, J., Younghusband, H. B., Green, R., Duff, A., Boltshauser, E., Grinspan, G. A., Dimon, J. H., Sibley, B. G., Andria, G., Toscano, E., Kerdraon, J., Bowsher, D., Pimstone, S. N., Samuels, M. E., Sherrington, R. and Hayden, M. R. . Clin. Genet. 2007; 4: 311-319. [BibTeX]
  • Additive effects of obesity and TCF7L2 variants on risk for type 2 diabetes among cardiac patients. Duan, Q. L., Dubé, M. P., Frasure-Smith, N., Barhdadi, A., Lesperance, F., Théroux, P., St-Onge, J., Rouleau, G. A. and McCaffery, J. M. . Diabetes Care 2007; 6: 1621-1623. [BibTeX]
  • Lamin A/C mutations associated with familial and sporadic cases of dilated cardiomyopathy in Koreans. Song, K., Dubé, M. P., Lim, J., Hwang, I., Lee, I. and Kim, J. J. . Exp. Mol. Med. 2007; 1: 114-120. [BibTeX]

2006

  • A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13. Levchenko, A., Provost, S., Montplaisir, J. Y., Xiong, L., St-Onge, J., Thibodeau, P., Rivière, J. B., Desautels, A., Turecki, G., Dubé, M. P. and Rouleau, G. A. . Neurology 2006; 5: 900-901. [BibTeX]
  • A new locus for autosomal dominant intracranial aneurysm, ANIB4, maps to chromosome 5p15.2-14.3. Verlaan, D. J., Dubé, M. P., St-Onge, J., Noreau, A., Roussel, J., Satgé, N., Wallace, M. C. and Rouleau, G. A. . J. Med. Genet. 2006; 6: e31. [BibTeX]
  • Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial. Mulligan, K., Parker, R. A., Komarow, L., Grinspoon, S. K., Tebas, P., Robbins, G. K., Roubenoff, R. and Dubé, M. P. . J. Acquir. Immune Defic. Syndr. 2006; 5: 590-597. [BibTeX]
  • Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. McCaffery, J. M., Frasure-Smith, N., Dubé, M. P., Théroux, P., Rouleau, G. A., Duan, Q. and Lespérance, F. . Psychosom Med 2006; 2: 187-200. [BibTeX]
  • Human monogenic disorders - a source of novel drug targets. Brinkman, R. R., Dubé, M. P., Rouleau, G. A., Orr, A. C. and Samuels, M. E. . Nat. Rev. Genet. 2006; 4: 249-260. [BibTeX]
  • Autism spectrum disorders associated with X chromosome markers in French-Canadian males. Gauthier, J., Joober, R., Dubé, M. P., St-Onge, J., Bonnel, A., Gariépy, D., Laurent, S., Najafee, R., Lacasse, H., St-Charles, L., Fombonne, E., Mottron, L. and Rouleau, G. A. . Mol. Psychiatry 2006; 2: 206-213. [BibTeX]

2005

  • Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. Dubé, M. P., Parker, R. A., Tebas, P., Grinspoon, S. K., Zackin, R. A., Robbins, G. K., Roubenoff, R., Shafer, R. W., Wininger, D. A., Meyer, W. A., Snyder, S. W. and Mulligan, K. . AIDS 2005; 16: 1807-1818. [BibTeX]
  • The effect of long-term storage on measured plasma lactate concentrations and prospective lactate results from a multicenter trial of antiretroviral therapy. Dubé, M. P., Kitch, D. W., Parker, R. A., Alston-Smith, B. L. and Mulligan, K. . Clin. Chem. Lab. Med. 2005; 9: 947-952. [BibTeX]
  • A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors. Duan, Q. L., Nikpoor, B., Dube, M. P., Molinaro, G., Meijer, I. A., Dion, P., Rochefort, D., Saint-Onge, J., Flury, L., Brown, N. J., Gainer, J. V., Rouleau, J. L., Agostoni, A., Cugno, M., Simon, P., Clavel, P., Potier, J., Wehbe, B., Benarbia, S., Marc-Aurele, J., Chanard, J., Foroud, T., Adam, A. and Rouleau, G. A. . Am. J. Hum. Genet. 2005; 4: 617-626. [BibTeX]
  • Chromosome 11-q24 region in Tourette syndrome: association and linkage disequilibrium study in the French Canadian population. Díaz-Anzaldúa, A., Rivière, J. B., Dubé, M. P., Joober, R., Saint-Onge, J., Dion, Y., Lespérance, P., Richer, F., Chouinard, S. and Rouleau, G. A. . Am. J. Med. Genet. A 2005; 3: 225-228. [BibTeX]
  • Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region. Shink, E., Harvey, M., Tremblay, M., Gagné, B., Belleau, P., Raymond, C., Labbé, M., Dubé, M. P., Lafrenière, R. G. and Barden, N. . Am. J. Med. Genet. B Neuropsychiatr. Genet. 2005; 1: 50-58. [BibTeX]